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SR 142948

SR 142948 Struktur
184162-64-9
CAS-Nr.
184162-64-9
Englisch Name:
SR 142948
Synonyma:
SR 142948;LWULHXVBLMWCHO-UHFFFAOYSA-N;inhibit,HT 29,Neurotensin Receptor,SR 142948,CHO cells,SR142948,SR-142948,dopamine,neurotensin,Inhibitor,psychotic disorders;2-[(5-(2,6-DIMETHOXY-PHENYL)-1-(4-[(3-DIMETHYLAMINO-PROPYL)-METHYL-CARBAMOYL]-2-ISOPROPYL-PHENYL)-1H-PYRAZOLE-3-CARBONYL)-AMINO]-ADAMANTANE-2-CARBOXYLIC ACID;2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID;2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID;TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID, 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-
CBNumber:
CB9787670
Summenformel:
C39H51N5O6
Molgewicht:
685.85214
MOL-Datei:
184162-64-9.mol

SR 142948 Eigenschaften

Siedepunkt:
824.7±65.0 °C(Predicted)
Dichte
1.29±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
Soluble to 75 mM in DMSO and to 25 mM in water
Aggregatzustand
Powder
pka
3.28±0.20(Predicted)
Farbe
White to off-white

Sicherheit

SR 142948 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SR 142948 is an antagonist of NT1/NT2 receptors inhibiting bile acid secretion. Neurotensin receptor antagonist.

Biologische Aktivit?t

Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC 50 = 0.32 - 3.96 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo .

SR 142948 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SR 142948 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Jinan Yaoyan Pharmaceutical Co., Ltd.
jnyaoyan@163.com China 3069 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com
meitaochem@126.com China 19103 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44807 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000
 jinoupharma@163.com China 11721 58
  • TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID, 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-
  • SR 142948
  • 2-[(5-(2,6-DIMETHOXY-PHENYL)-1-(4-[(3-DIMETHYLAMINO-PROPYL)-METHYL-CARBAMOYL]-2-ISOPROPYL-PHENYL)-1H-PYRAZOLE-3-CARBONYL)-AMINO]-ADAMANTANE-2-CARBOXYLIC ACID
  • 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
  • LWULHXVBLMWCHO-UHFFFAOYSA-N
  • inhibit,HT 29,Neurotensin Receptor,SR 142948,CHO cells,SR142948,SR-142948,dopamine,neurotensin,Inhibitor,psychotic disorders
  • 2-[[[5-(2,6-DIMETHOXYPHENYL)-1-[4-[[[3-(DIMETHYLAMINO)PROPYL]METHYLAMINO]CARBONYL]-2-(1-METHYLETHYL)PHENYL]-1H-PYRAZOL-3-YL]CARBONYL]AMINO]-TRICYCLO[3.3.1.13,7]DECANE-2-CARBOXYLIC ACID
  • 184162-64-9
  • C39H51N5O6
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