2-Bromo-3-fluoronitrobenzene
|
|
|
- CAS-Nr.
- 59255-94-6
- Englisch Name:
- 2-Bromo-3-fluoronitrobenzene
- Synonyma:
- 2-Bromo-1-fluoro-3-nitrobenzene;2-broMo-3-fluorobroMobezene;2-BROMO-3-FLUORONITROBENZENE;1-Bromo-2-fluoro-6-nitrobenzene;Benzene, 2-bromo-1-fluoro-3-nitro-;2-Bromo-3-fluoronitrobenzene ISO 9001：2015 REACH
- CBNumber:
- CB9783955
- Summenformel:
- C6H3BrFNO2
- Molgewicht:
- 220
- MOL-Datei:
- 59255-94-6.mol
|
2-Bromo-3-fluoronitrobenzene Eigenschaften
- Schmelzpunkt:
- 42.0-44.0 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
- Siedepunkt:
- 222.3±20.0 °C(Predicted)
- Dichte
- 1.808±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Aggregatzustand
- solid
- Farbe
- yellow
- CAS Datenbank
- 59255-94-6(CAS DataBase Reference)
2-Bromo-3-fluoronitrobenzene Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
Preparation method of 2-bromo-3-fluoronitrobenzene: Add 21.6g (0.1mol) 2-bromo-3-nitroaniline, 12.5ml (0.15mol) concentrated hydrochloric acid, and 12.5ml water into a reaction bottle, and reduce the temperature to 15°C; dissolve 8.3g (0.12mol) sodium nitrite in 14.5ml water and slowly add dropwise to the above system, then add 11.4g (0.13mol) fluoroboric acid, keep warm at 15°C and stir for 2 hours, track the reaction by HPLC until the reaction of 2-bromo-3-nitroaniline is complete; filter, rinse the filter cake with methanol, and dry to obtain 25.8g of intermediate IV. Add 30 ml of toluene to the reaction flask, heat to 100 ° C, slowly add 10 g (31.7 mmol) of intermediate IV, keep warm and stir for 1 hour, track the reaction by HPLC until the intermediate IV reacts completely: concentrate, recrystallize from ethyl acetate and n-hexane to obtain 5.7 g of 2-Bromo-3-fluoronitrobenzene, with a molar yield of 83%.
2-Bromo-3-fluoronitrobenzene Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Bromo-3-fluoronitrobenzene Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 175)Lieferanten
59255-94-6()Verwandte Suche:
- 2-BROMO-3-FLUORONITROBENZENE
- 2-broMo-3-fluorobroMobezene
- Benzene, 2-bromo-1-fluoro-3-nitro-
- 2-Bromo-3-fluoronitrobenzene ISO 9001：2015 REACH
- 2-Bromo-1-fluoro-3-nitrobenzene
- 1-Bromo-2-fluoro-6-nitrobenzene
- 59255-94-6
- blocks
- Bromides
- FluoroCompounds
- NitroCompounds
