DC-CHOL Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
DC-Chol is a cationic cholesterol derivative. DC-Chol, as a component of lipoplexes with DOPE , has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.
Verwenden
DC-Cholesterol HCl is suitable:
- for the preparation of ultrasound cationic microbubbles
- to prepare liposomes
- for the preparation of L-glutathione (GSH), loaded proliposomes
Allgemeine Beschreibung
DC-Cholesterol HCl is a sterol-based transfection reagent.
DC-CHOL Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte