GUAYEWUANINE B
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Sicherheit
GUAYEWUANINE B Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
A aconite alkaloid present in Aconitum fischeri Reich, A. sachalinense, Fr. Schmidt (Saghalien) and A. subcuneaturn, Nakai, this base is amorphous but yields crystalline salts, e.g. the perchlorate, m.p. 230-2°C (dec.); aurich10ride, m.p. 208-9°C (dec.) and a perbromide, m.p. 181-2°C (dec.). Boiling dilute H2S04 causes hydrolysis with the production of acetic acid and jesanisaconine (p-anisoylaconine) forming a crystalline hydrochloride, m.p. 209- 21 O°C (dec.).Alkaline hydrolysis gives acetic and p-anisic acids and aconine. Pyrolysis furnishes pyrojesaconitine, obtained as the crystalline perchlorate, m.p. 171-2°C; [α]13D - 27.4° (MeOH). Oxidation with KMn04 yields acetaldehyde, indicative of an ethylimino group. The structure of the alkaloid has been determined by con_x0002_tinuous monitoring of the pyrolysis and an examination of the products produced.Jesaconitine is, like all of the aconitines, highly toxic producing raspiratory paralysis and a direct toxic action on the heart, the latter often terminating in ventricular fibrillation.
Occurrence
A complex aconitine alkaloid, yunaconitine has been isolated from Aconitum hemsJeyanum.Einzelnachweise
Makoshi., Arch. Pharm., 247,243 (1909)Majima, Suginome, Morio., Ber., 57B, 1486 (1924)
Majima, Morio.,Annalen., 476,171,194,203 (1929)
Tamura., ibid, 533,183 (1937)
Structure:
Keith, Pelletier., Chem. Commun., 993 (1967)
Keith, Pelletier., ibid, 161 (1968)
Keith, Pelletier., 1. Org. Chem., 33, 2497 (1968)
GUAYEWUANINE B Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
GUAYEWUANINE B Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 12)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
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Scandinavian Formulas | -- |
mikep@scandinavianformulas.com | United States | 1550 | 58 |
United States Biological | -- |
chemicals@usbio.net | United States | 6214 | 80 |
Shanghai Xuanya Biotechnology Co., Ltd. | -- |
1517347860@qq.com | CHINA | 6673 | 58 |
Shanghai Yuanmu Biological Technology Co., Ltd. | -- |
CHINA | 6179 | 58 | |
Guangzhou Weijia Technology Co., Ltd. | -- |
WHIGA22@126.COM | CHINA | 6748 | 58 |
Shanghai Weiwei Biological Technology Co., Ltd. | -- |
sales@wheybio.com | CHINA | 4398 | 58 |
Shanghai Hao Zhun Biological Technology Co., Ltd. | -- |
info@zzsrm.com | CHINA | 6650 | 58 |
Shanghai Yuda Industrial Co., Ltd. | -- |
lucy@runwelltac.com | CHINA | 6105 | 58 |
Shenzhen Medherb Biotecnology Co., Ltd. | -- |
sales@medherb.cn | China | 46 | 50 |
Advanced Technology & Industrial Co., Ltd. | -- |
sales@advtechind.com | China | 6523 | 75 |