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BAY 299

BAY 299 Struktur
2080306-23-4
CAS-Nr.
2080306-23-4
Englisch Name:
BAY 299
Synonyma:
CPD1617;BAY 299;BAY-299; BAY 299; BAY299;6-(3-hydroxypropyl)-2-(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione;6-(3-Hydroxy-propyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzo[de]isoquinoline-1,3-dione;6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-;6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;8-(3-hydroxypropyl)-3-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3-azatricyclo[7.3.1.0?,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione
CBNumber:
CB93381026
Summenformel:
C25H23N3O4
Molgewicht:
429.47
MOL-Datei:
2080306-23-4.mol

BAY 299 Eigenschaften

Siedepunkt:
688.7±55.0 °C(Predicted)
Dichte
1.377±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:30.0(Max Conc. mg/mL);69.85(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);69.85(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
14.98±0.10(Predicted)
Farbe
Light yellow to yellow

Sicherheit

BAY 299 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BAY-299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 (IC50 = 6 nM), also known as BRPF2, and the second bromodomain of transcription initiation factor TFIID subunits 1 (TAF1; IC50 = 13 nM). BAY-299 is >30-fold selective over BRPF1, BRPF3, BRD9, and ATAD2 and is >300-fold selective over BRD4. See the Structural Genomics Consortium (SGC) website for more information.

BAY 299 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BAY 299 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 51)Lieferanten
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  • BAY-299; BAY 299; BAY299
  • 6-(3-hydroxypropyl)-2-(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione
  • BAY 299
  • CPD1617
  • 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • 1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-
  • 6-(3-Hydroxy-propyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-benzo[de]isoquinoline-1,3-dione
  • 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
  • 8-(3-hydroxypropyl)-3-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3-azatricyclo[7.3.1.0?,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione
  • 2080306-23-4
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