TILUDRONIC ACID, DISODIUM SALT
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- CAS-Nr.
- 149845-07-8
- Englisch Name:
- TILUDRONIC ACID, DISODIUM SALT
- Synonyma:
- SKELID;SR-41319B;SR 41319G;Unii-bh6m93cia0;Tiludrote disodium;DisodiuM Tiludronate;DisodiumTiludronate>TILUDRONIC ACID, DISODIUM SALT;Disodium (4-chlorophenylthio)methylenediphosphonate;(((4-chlorophenyl)thio)methylene)diphosphonic acid, sodium salt
- CBNumber:
- CB9288177
- Summenformel:
- C7H10ClNaO6P2S
- Molgewicht:
- 342.6
- MOL-Datei:
- 149845-07-8.mol
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TILUDRONIC ACID, DISODIUM SALT Eigenschaften
- Schmelzpunkt:
- >300°C
- storage temp.
- -20°C Freezer
- L?slichkeit
- Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Merck
- 14,9441
TILUDRONIC ACID, DISODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Tiludronate disodium, the first of the third generation of bisphosphonates, was
introduced to the market in Switzerland for the treatment of Paget‘s disease.
Bisphosphonates have high affinity for bone. When given orally, they are not
metabolized but are absorbed, stored, preferentially localized to the skeleton where
they inhibit bone resorption and therefore are useful in the treatment of diseases of high
bone turnover such as Paget’s disease and hypercalcemia of malignancy.
Mechanistically, tiludronate disodium is suggested to be a specific inhibitor of
functioning osteoclasts through selective incorporation into the polarized osteoclastlike
multinucleated cells and direct interference with the maintenance of the
cytoskeletal structure. Tiludronate disodium is reportedly in clinical trials for
osteoporosis in post-menopausal women.
Chemische Eigenschaften
Fine White to Off-White Crystalline Powder
Verwenden
A biphosphonate bone resorption inhibitor.
TILUDRONIC ACID, DISODIUM SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
TILUDRONIC ACID, DISODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 66)Lieferanten
149845-07-8()Verwandte Suche:
- Disodium (4-chlorophenylthio)methylenediphosphonate
- SR-41319B
- SKELID
- TILUDRONIC ACID, DISODIUM SALT
- [[(4-CHLOROPHENYL)THIO]METHYLENE]BIPHOSPHONIC ACID, DISODIUM SALT
- [[(4-Chlorophenyl)thio]methylene]biphosphonicAcid,DisodiumSalt,SR-41319B,Skelid
- Unii-bh6m93cia0
- DisodiuM Tiludronate
- SR 41319G
- DisodiumTiludronate>
- Tiludrote disodium
- Disodium [[(4-Chlorophenyl)thio]methylene]bis(hydrogenphosphonate)
- (((4-chlorophenyl)thio)methylene)diphosphonic acid, sodium salt
- 149845-07-8
- C7H7ClNa2O6P2S
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Phosphorylating and Phosphitylating Agents
