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Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Struktur
117337-19-6
CAS-Nr.
117337-19-6
Englisch Name:
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
Synonyma:
kih-9201;Hsdb 7270;FLUTHIACET-METHYL;Eluthiacet-methyl;Semaglutide Impurity 9;Fluthiacet-methyl [iso];Fluthiacet-methyl Standard;Fluthiacet-methyl Solution;1000 μg/mL in Acetonitrile;C13862000 Fluthiacet-methyl
CBNumber:
CB9232165
Summenformel:
C15H15ClFN3O3S2
Molgewicht:
403.88
MOL-Datei:
117337-19-6.mol

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Eigenschaften

Schmelzpunkt:
104.6°
Siedepunkt:
503.5±60.0 °C(Predicted)
Dichte
1.57±0.1 g/cm3(Predicted)
storage temp. 
0-6°C
pka
-2.86±0.20(Predicted)
BRN 
11510131
EPA chemische Informationen
Fluthiacet-methyl (117337-19-6)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,N
R-S?tze: 36-50
S-S?tze: 26-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
HS Code  29309090
Giftige Stoffe Daten 117337-19-6(Hazardous Substances Data)
Toxizit?t LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Miyazawa)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H400 Sehr giftig für Wasserorganismen. Kurzfristig (akut) gew?ssergef?hrdend Kategorie 1 Warnung GHS hazard pictogramssrc="/GHS09.jpg" width="20" height="20" /> P273, P391, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Herbicide.

Stoffwechselwegen

Fluthiacet methyl is converted to its isomer, urazole, by glutathione S-transferase (GST) and glutathione (GSH) from some plants and rat liver microsomes. Fluthiacet methyl inhibits Protox (protoporphyrinogen oxidase) activity after conversion to the corresponding urazole by GST and GSH. Fluthiacet methyl is chemically converted to urazole with a thiol anion in media by the nucleophilic reaction. It is also suggested that a free acid of urazole, desulfated urazole, and the oxidative ring-cleaved formyl degradation products result from hydrolysis with esterase from soybean seedlings.
When fluthiacet methyl is administered orally to rats in a single dose, 63-85% of the dose is excreted in the feces and 10-23% in the urine, respectively, after 48 h. The main metabolite is the isomer of fluthiacet methyl (urazole) which is also identified in the soil degradation products. Monohydroxylated products on the pyridazine ring are identified as metabolites by rats only.

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 47)Lieferanten
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Hangzhou FandaChem Co.,Ltd.
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GIHI CHEMICALS CO.,LIMITED
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
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Alta Scientific Co., Ltd. 022-6537-8550 15522853686
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Shandong Xiya Chemical Co., Ltd. 4009903999 13395398332
sales@xiyashiji.com China 20806 60

  • FLUTHIACET-METHYL
  • Methyl {2-chloro-4-fluoro-5-[(EZ)-5,6,7,8-tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylideneamino]phenylthio}acetate
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-yliden
  • Acetic acid, ((2-chloro-4-fluoro-5-((tetrahydro-3-oxo-1H,3H-(1,3,4)thiadiazolo(3,4-A)pyridazin-1-ylidene)amino)phenyl)thio)-, methyl ester
  • Fluthiacet-methyl [iso]
  • Hsdb 7270
  • fluthiacet-methyl (bsi, pa iso)
  • kih-9201
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
  • Eluthiacet-methyl
  • [[2-Chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo [3,4-a]pyridazin-1-ylidine)amino]phenyl]thioacetic acid methyl ester
  • Fluthiacet-methyl Standard
  • Fluthiacet-methyl Solution, 1000ppm
  • Acetic acid, 2-[[2-chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]thio]-, methyl ester
  • Fluthiacet-methyl Solution
  • 1000 μg/mL in Acetonitrile
  • Fluthiacet-methyl Solution in Methanol, 100μg/mL
  • C13862000 Fluthiacet-methyl
  • Fluthiacet-methyl in Acetonitrile
  • Semaglutide Impurity 9
  • 117337-19-6
  • C15H15ClFN3O3S2
  • Cl5H15ClFN3O3S2
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