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epsilon-viniferin

epsilon-viniferin Struktur
62218-08-0
CAS-Nr.
62218-08-0
Englisch Name:
epsilon-viniferin
Synonyma:
e-viniferin;Ε-VINIFERIN;ε-Viniferin-RM;epsilon-viniferin;trans-ε-Viniferin;epsilion-Viniferin;ε-Viniferin Standard;(-)-trans-ε-viniferin;(-)-trans-epsilon-viniferin;ε ?Viniferin,ε-?Viniferin,Inhibitor,inhibit,Cytochrome P450,CYPs,ε?Viniferin
CBNumber:
CB91337184
Summenformel:
C28H22O6
Molgewicht:
454.47
MOL-Datei:
62218-08-0.mol

epsilon-viniferin Eigenschaften

Schmelzpunkt:
approximate 157℃ (dec.)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in methanol;
Aggregatzustand
Powder
Farbe
Off-white to gray
Wasserl?slichkeit
sparingly soluble in water
LogP
3.802 (est)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

epsilon-viniferin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines and has diverse biological activities. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42; ) fibrils in a cell-free assay and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells (EC50 = 30 nM). It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells (IC50 = ~1 μM). In vivo, trans-ε-viniferin (2 μg per animal) reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.

Verwenden

ε-Viniferin is a stilbene extract posessing cytotoxic effects and may contain anti-cancer properties.

epsilon-viniferin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


epsilon-viniferin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 69)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Shanghai Standard Technology Co., Ltd.
18502101150
ft-sales@nature-standard.com CHINA 1923 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32063 58
Aktin Chemicals, Inc.
028-85159085
info@aktinchem.com CHINA 1025 58
Labnetwork lnc.
+86-27-50766799 +8618062016861
contact@labnetwork.com China 19987 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38463 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Mensura Group Limited
+8618109034517
hkd008@vacorda.com China 2900 58
Chembest Research Laboratories Limited +86-21-20908456
sales@BioChemBest.com China 6005 61

62218-08-0()Verwandte Suche:


  • epsilon-viniferin
  • (-)-5-[[(2R)-2,3-Dihydro-6-hydroxy-2β-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)vinyl]benzofuran]-3α-yl]-1,3-benzenediol
  • (2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-(4-hydroxy-trans-styryl)-2,3-dihydrobenzofuran-6-ol
  • (2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-4-hydroxystyryl]-2,3-dihydrobenzofuran-6-ol
  • [2R,(-)]-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-6-ol
  • 5-[(2R,3R)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-3-yl]benzene-1,3-diol
  • e-viniferin
  • (-)-trans-epsilon-viniferin
  • epsilion-Viniferin
  • Ε-VINIFERIN
  • ε-Viniferin Standard
  • trans-ε-Viniferin
  • 1,3-Benzenediol, 5-[(2R,3R)-2,3-dihydro-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1E)-2-(4-hydroxyphenyl)ethenyl]-3-benzofuranyl]-
  • (-)-trans-ε-viniferin
  • 5-[(2R,3R)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol
  • ε ?Viniferin,ε-?Viniferin,Inhibitor,inhibit,Cytochrome P450,CYPs,ε?Viniferin
  • 5-((2R,3R)-6-Hydroxy-2-(4-hydroxyphenyl)-4-((E)-4-hydroxystyryl)-2,3-dihydrobenzofuran-3-yl)benzene-1,3-diol
  • ε-Viniferin-RM
  • 62218-08-0
  • 62218-08-8
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