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Tigemonam

Tigemonam Struktur
102507-71-1
CAS-Nr.
102507-71-1
Englisch Name:
Tigemonam
Synonyma:
Tigemom;SQ-30213;Tigemonam;Antibiotic SQ-30213;[[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci;Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-;Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
CBNumber:
CB91179920
Summenformel:
C12H15N5O9S2
Molgewicht:
437.41
MOL-Datei:
102507-71-1.mol

Tigemonam Eigenschaften

Dichte
1.91±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
pka
-3?+-.0.18(Predicted)

Sicherheit

Tigemonam Chemische Eigenschaften,Einsatz,Produktion Methoden

Clinical Use

Tigemonam is a newer monobactam that is orally active.It is highly resistant to β-lactamases. The antibacterialspectrum of activity resembles that of aztreonam. It is veryactive against the Enterobacteriaceae, including E. coli,Klebsiella, Proteus, Citrobacter, Serratia, and Enterobacterspp. It also exhibits good potency against H. influenzae andN. gonorrhoeae. Tigemonam is not particularly activeagainst Gram-positive or anaerobic bacteria and is inactiveagainst P. aeruginosa.
In contrast to the poor oral bioavailability of aztreonam,the oral absorption of tigemonam is excellent. Itcould become a valuable agent for the oral treatment ofurinary tract infections and other non–life-threatening infectionscaused by β-lactamase–producing Gram-negativebacteria.

Tigemonam Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tigemonam Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 12)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4861 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
liming@bio-fount.com China 9729 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946
1461866103@qq.com China 16111 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Hubei Chenghai Chemical Co., Ltd 18327245847 18327245847
1400838877@qq.com China 9960 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11974 58
RD International Technology Co., Limited 18024082417
market@ubiochem.com China 9266 58

102507-71-1()Verwandte Suche:


  • Tigemonam
  • [[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid
  • Antibiotic SQ-30213
  • SQ-30213
  • Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
  • Tigemom
  • Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-
  • 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci
  • 102507-71-1
  • C12H15N5O9S2
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