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Piriprost

Piriprost Struktur
79672-88-1
CAS-Nr.
79672-88-1
Englisch Name:
Piriprost
Synonyma:
U-60257;Piriprost;Piriprostium;Unii-R802o5nilk;Piriprostium [latin];(4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(E,S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid;(4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid;Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-((1E,3S)-3-hydroxy-1-octenyl)-1-phenyl-, (4R,5R)-;Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenyl-, (4R-(4alpha(1E,3S*),5beta))-
CBNumber:
CB91179531
Summenformel:
C26H35NO4
Molgewicht:
425.565
MOL-Datei:
79672-88-1.mol

Piriprost Eigenschaften

Sicherheit

Piriprost Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-asthmatic.

Enzyminhibitor

This lipoxygenase-inhibiting pyrrole analogue of prostacyclin (FWpotassium salt = 463.66 g/mol; CAS 79672-88-1), also known as U60257B and 6,9- deepoxy-6,9-(phenylimino)-D6,8-prostaglandin I1, [4R-[4a(1E,3S*),5b]]- 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenylcyclopenta[ b]pyrrole-2-pentanoate, inhibits leukotriene C and D formation.1-5 Piriprost also inhibits the release of histamine and leukotrienes from isolated porcine lung cells.6 Note that both priprost and its methyl ester (U-56467) inhibit leukotriene biosynthesis: ID50 = 4.6 and 0.31 μM, respectively. Target(s): glutathione S-transferase; and 5- lipoxygenase, or arachidonate 5-lipoxygenase.

Piriprost Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Piriprost Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19885 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 19704 58

  • (4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid
  • (4R)-1,4,5,6-Tetrahydro-5α-hydroxy-4β-[(E,S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-pentanoic acid
  • U-60257
  • Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-((1E,3S)-3-hydroxy-1-octenyl)-1-phenyl-, (4R,5R)-
  • Cyclopenta(B)pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenyl-, (4R-(4alpha(1E,3S*),5beta))-
  • Piriprostium
  • Piriprostium [latin]
  • Unii-R802o5nilk
  • Piriprost
  • 79672-88-1
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