Varenicline tartrate
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- CAS-Nr.
- 375815-87-5
- Englisch Name:
- Varenicline tartrate
- Synonyma:
- CS-291;Champix;Pidifix330;Pidifix-330;CP 526555-18;Unii-82269asb48;ChaMpix tartrate;Chantix tartrate;Varniclan tartrate;Varenicline tatrate
- CBNumber:
- CB91011765
- Summenformel:
- C17H19N3O6
- Molgewicht:
- 361.35
- MOL-Datei:
- 375815-87-5.mol
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Varenicline tartrate Eigenschaften
- Schmelzpunkt:
- 206-208°C
- storage temp.
- room temp
- L?slichkeit
- DMSO: >5mg/mL
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Hygroscopic
- InChI
- InChI=1/C13H13N3.C4H6O6/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1;5-1(3(7)8)2(6)4(9)10/h1-2,4-5,8-9,14H,3,6-7H2;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/s3
- InChIKey
- TWYFGYXQSYOKLK-UHFFFAOYSA-N
- SMILES
- [C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C12=CC3=NC=CN=C3C=C1C1CNCC2C1 |&1:0,5,r|
Varenicline tartrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Tan Solid
Verwenden
Varenicline tartrate is a prescription medication used to treat smoking addiction. Varenicline is a nicotinic receptor partial agonist. In this respect, it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement ther
Definition
ChEBI: A tartrate salt obtained by reaction of varenicline with one equivalent of (R,R)-tartaric acid. A partial agonist for nicotinic cholinergic receptors, it is used as an aid to giving up smoking.
Biologische Aktivit?t
Orally active, subtype-selective partial agonist at α 4 β 2 nicotinic receptors (K i values are 0.06, 240, 322 and 3540 nM for α 4 β 2, α 3 β 4, α 7, α 1 β γ δ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo .
Varenicline tartrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Varenicline tartrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 326)Lieferanten
375815-87-5()Verwandte Suche:
- VARENICLINE TARTRATE
- Varenicline tartrate for research
- 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (2R,3R)-2,3- dihydroxybutanedioate
- Champix
- CP 526555-18
- ,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-
- 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepinetartrate
- 6,10-Methano-6H-pyrazino(2,3-H)(3)benzazepine, 7,8,9,10-tetrahydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
- Unii-82269asb48
- 7,8,9,10-Tetrahydro-
- ChaMpix tartrate
- Chantix tartrate
- Varenicline tatrate
- 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-, (2R,3R)-2,3-dihydroxybutanedioate
- Varenicline tartrate solution
- 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino-[4,5-g]quinoxaline (2R,3R)-2,3-dihydroxysuccinate
- Varenicline Tartarate
- CS-291
- 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline (2R,3R)-2,3-Dihydroxysuccinic Acid
- Varenicline tartrate USP/EP/BP
- Varenicline Tartrate
DISCONTINUED
- Varenicline Tartrate (CP 526555-18)
- Pidifix330
- Pidifix-330
- TLF3617 Pidifix 330
- Varniclan tartrate
- Vernicline Tartrate API
- 375815-87-5
- 75815-87-5
- C13H13N3C4H6O6
- Heterocycles
- Intermediates & Fine Chemicals
- Heterocyclic Compounds
- Inhibitors
- Chantix, Champix
- APIs
- Pfizer compounds
- Pharmaceuticals
