Etomidolin
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Etomidolin Eigenschaften
- Schmelzpunkt:
- 106-107°
- Siedepunkt:
- 507.34°C (rough estimate)
- Dichte
- 1.1315 (rough estimate)
- Brechungsindex
- 1.6500 (estimate)
- pka
- 8.75±0.10(Predicted)
Sicherheit
Toxizit?t | LD50 in mice (mg/kg): 176 orally; 44.8 i.v. (Giraldi, Mariotti, 1971) |
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Etomidolin Chemische Eigenschaften,Einsatz,Produktion Methoden
Originator
Smedolin,Yamanouchi,Japan,1976Manufacturing Process
31.3 g of 1-oxo-3-(aminophenyl-p-ethoxypiperidino)-isoindoline (0.0892 mol) are dissolved in 500 ml of anhydrous N,N-dimethylformamide. To this solution 5.75 g of NaH (0.105 mol) and 7.24 ml of CH2CH2I (0.0945 mol) are added and the resulted mixture is heated at 70°C for 1 hour, and then poured into an excess of water. 1-oxo-2-ethyl-3-(aminophenyl-p-ethoxypiperidino)- isoindoline (MP 106°C to 107°C) is obtained by crystallization with ligroin.1-oxo-2-ethyl-3-(iminophenyl-p-ethoxypiperidino)-isoindoline (MP 103°C to 104°C) is obtained as a byproduct with the above compound. This latter compound was reduced to produce 1-oxo-2-ethyl-3-(aminophenyl-p-ethoxypiperidino)-isoindoline.
Therapeutic Function
Muscle relaxantEtomidolin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Etomidolin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 4)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
TargetMol Chemicals Inc. | +8613564774135 |
zijue.cai@tsbiochem.com | United States | 19885 | 58 |
TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 19704 | 58 |
21590-92-1(Etomidolin)Verwandte Suche:
- etomidoline
- 1H-Isoindol-1-one, 2-ethyl-2,3-dihydro-3-[[4-[2-(1-piperidinyl)ethoxy]phenyl]amino]-
- Amidoline
- K 2680
- Nonspa
- Phthalimidine, 2-ethyl-3-(β-piperidino-p-phenetidino)- (8CI)
- Smedolin
- 2-Ethyl-2,3-dihydro-3-[[4-[2-(1-piperidinyl)ethoxy]phenyl]amino]-1H-isoindol-1-one
- 2-Ethyl-2,3-dihydro-3-[4-(2-piperidinoethoxy)anilino]-1H-isoindol-1-one
- 21590-92-1