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LY 344864

LY 344864 Struktur
186544-26-3
CAS-Nr.
186544-26-3
Englisch Name:
LY 344864
Synonyma:
CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;LY 344864 hydrochloride, 5-HT1F agonist;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
CBNumber:
CB8847478
Summenformel:
C21H22FN3O
Molgewicht:
351.42
MOL-Datei:
186544-26-3.mol

LY 344864 Eigenschaften

Siedepunkt:
471.9±45.0 °C(Predicted)
Dichte
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
DMSO : ≥ 350 mg/mL (995.96 mM)
pka
14.12±0.40(Predicted)
Aggregatzustand
Powder
Farbe
White to off-white
Wasserl?slichkeit
water: 10mM
DMSO: 100mM

Sicherheit

LY 344864 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

LY 344864 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LY 344864 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 62)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32965 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29810 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 24727 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19881 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 94657 76
  • LY 344864
  • LY 344864 hydrochloride
  • N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
  • (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
  • (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
  • LY344864 HCL
  • LY344864;LY-344864
  • CS-660
  • Y344864
  • Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
  • migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F
  • LY 344864 hydrochloride, 5-HT1F agonist
  • 186544-26-3
  • C21H22N3OFHCl
  • Inhibitors
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