PLECONARIL
|
|
|
- CAS-Nr.
- 153168-05-9
- Englisch Name:
- PLECONARIL
- Synonyma:
- Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
- CBNumber:
- CB8840318
- Summenformel:
- C18H18F3N3O3
- Molgewicht:
- 381.35
- MOL-Datei:
- 153168-05-9.mol
|
PLECONARIL Eigenschaften
- Schmelzpunkt:
- 61-62°
- Siedepunkt:
- 481.2±55.0 °C(Predicted)
- Dichte
- 1.271
- storage temp.
- room temp
- L?slichkeit
- DMSO: ≥10mg/mL (warmed)
- Aggregatzustand
- powder
- pka
- -1.33±0.10(Predicted)
- Farbe
- white to beige
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
|
|
| R-S?tze: |
25 |
|
|
| S-S?tze: |
45 |
|
|
| RIDADR |
UN 2811 6.1 / PGIII |
|
|
| WGK Germany |
3 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
| H413 |
Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 4 |
|
|
|
|
| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
|
PLECONARIL Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-White Solid
Verwenden
Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.
Allgemeine Beschreibung
Pleconaril is a drug, that has antiviral activity.
Pharmazeutische Anwendungen
An oxadiazole active against most enteroviruses and rhinoviruses.
It binds to the hydrophobic pocket of the virus capsid
protein VP1, inducing conformational changes that lead to
altered receptor binding and viral uncoating. Concerns over
safety and efficacy have constrained development of the drug.
PLECONARIL Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PLECONARIL Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 99)Lieferanten
- WIN 63843
- 3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
- Picovir
- 3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
- 1,2,4-Oxadiazole,3-[3,5-diMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
- VP 63843
- 3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole
- Rimiducid
- PLECONARIL
- Pleconarilis
- 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole
- Pleconaril-d4
- PLECONARIL USP/EP/BP
- Pleconaril VP-63843 Win-63843
- 153168-05-9
- Anti-virals
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- API
