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Dolutegravir Impurity 8

Dolutegravir Impurity 8 Struktur
2244161-72-4
CAS-Nr.
2244161-72-4
Englisch Name:
Dolutegravir Impurity 8
Synonyma:
Dolutegravir Impurity 59;2,6-Di fluoro Dolutegravir;Dolutegravir 2,6-difluoro Impurity;2,6 Difluoro dolutegravir sodium salt;1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB88117623
Summenformel:
C20H19F2N3O5
Molgewicht:
419.38
MOL-Datei:
2244161-72-4.mol

Dolutegravir Impurity 8 Eigenschaften

Siedepunkt:
664.9±55.0 °C(Predicted)
Dichte
1.53±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)

Sicherheit

Dolutegravir Impurity 8 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity 8 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir Impurity 8 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CR Corporation Limited 		+8613062833949
 fred.wen@crcorporation.cn China 8647 58
sgtlifesciences pvt ltd 		+8617013299288
 dj@sgtlifesciences.com China 12373 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522
 overseasales@yongstandards.com China 11922 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422
 sale@hdimpurity.com China 3389 58
Shenzhen Roark Pharma-Tec Co., Ltd. 13128912434
 2880126944@qq.com China 2577 58
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657
 sales@bjcomparison.com China 4937 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
 greensnown@163.com China 9906 50
Hubei Yangxin Medical Technology Co., Ltd. 15374522761
 3003392093@qq.com China 8368 55
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd. 020-89854820
sales@jzpharma.cn China 1080 58
Nanjing zehe Pharmaceutical Technology Co., Ltd 17768115366
 henry124604479@163.com China 251 58
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
  • 2,6-Di fluoro Dolutegravir
  • Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity)
  • 4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir
  • 2,6 Difluoro dolutegravir sodium salt
  • (4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • Dolutegravir 2,6-difluoro Impurity
  • Dolutegravir Impurity 59
  • 1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-
  • 2244161-72-4
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