(R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol)
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- CAS-Nr.
- 84-16-2
- Bezeichnung:
- (R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol)
- Englisch Name:
- HEXESTROL
- Synonyma:
- Hexron;Estrifar;Estronal;NSC-9894;Synthovo;Sinestrol;Synestrol;Vitestrol;HEXOESTROL;Estra-Plex
- CBNumber:
- CB8758929
- Summenformel:
- C18H22O2
- Molgewicht:
- 270.37
- MOL-Datei:
- 84-16-2.mol
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(R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol) Eigenschaften
- Schmelzpunkt:
- 186 °C
- Siedepunkt:
- 353.48°C (rough estimate)
- Dichte
- 1.093
- Brechungsindex
- 1.4800 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- almost transparency in Methanol
- pka
- 9.80±0.26(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Almost white
- Merck
- 14,4701
- BRN
- 3209460
- InChI
- InChI=1/C18H22O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,17-20H,3-4H2,1-2H3/t17-,18+
- InChIKey
- PBBGSZCBWVPOOL-HDICACEKNA-N
- SMILES
- [C@@H](C1=CC=C(O)C=C1)(CC)[C@@H](C1=CC=C(O)C=C1)CC |&1:0,10,r|
- CAS Datenbank
- 84-16-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H350 |
Kann Krebs verursachen. |
Karzinogenit?t |
Kategorie 1A |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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(R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol) Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R45:Kann Krebs erzeugen.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Crystalline Solid
Verwenden
Estrogen; antineoplastic (hormonal).
l?uterung methode
Crystallise meso-Hexestero from *benzene or aqueous EtOH (m 185-188o). The meso-dibenzoyl derivative has m 236-237o. The 3RS,4RS(±)-racemate [5776-72-7] crystallises from pet ether, *C6H6/pet ether, Et2O/pet ether, or MeOH/H2O and has m 128-129o . The (±)-dibenzoyl derivative has m 123-124o . The 3R,4R(+)-isomer [26614-21-1] and 3S,4S(-)-isomer [26614-22-2] crystallise from Et2O/pet ether with m 80 -80.5o and have [] D (+) and (-) 17.7o (c 5, EtOH). Their dibenzoyl derivatives have m 116.5o .[Beilstein 6 III 5503, 6 IV 6761.] They have estrogenic activity where optically active forms are more potent and they have antineoplastic activity. [Aboul-Enein et al. Anal Profiles Drug Subst 11 347 1982, J Am Chem Soc 65 4911941.]
(R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 168)Lieferanten
84-16-2((R*,S*)-4,4'-(1,2-diethylethylen)bis(phenol))Verwandte Suche:
- Hexanoestrol Solution, 100ppm
- Hexestrol solution,100ppm
- Hexoestrol
- Hexestrol(Bibenzyl)
- 4,4'-(hexane-3,4-diyl)diphenol
- Phenol,4,4'-[(1R,2S)-1,2-diethyl-1,2-ethanediyl]bis-, rel-
- 4,4’-(1,2-diethyl-1,2-ethanediyl)bis-,(r*,s*)-pheno
- 4,4’-(1,2-diethyl-1,2-ethanediyl)bis-phenol
- 4,4’-(1,2-diethyl-1,2-ethylenediyl)bis-,(r*,s*)-pheno
- 4,4’-dihydroxy-alpha,beta-diethyldiphenylethane
- 4,4’-dihydroxy-gamma,delta-diphenylhexane
- 4,4'-Dihydroxy-alpha,beta-diethyldiphenylethane
- 4,4'-Dihydroxy-gamma,delta-diphenylhexane
- 4’-(1,2-diethylethylene)di-meso-pheno
- alpha,alpha’-diethyl-4,4’-dihydroxy-bibenzy
- 3,4-bis(p-hydroxyphenyl)-hexan
- 4,4'-(1,2-DIETHYLETHYLENE)DIPHENOL
- MESO-3,4-BIS[4-HYDROXYPHENYL]-HEXANE
- DIHYDRODIETHYLSTILBESTROL
- HEXOESTROLUM
- HEXOESTROL
- (R*,S*)-4,4'-(1,2-diethylethylene)bis(phenol)
- HEXESTEROL VETRANAL, 250 MG
- DL-HEXESTROL
- MESO-HEXOESTROL
- 4,4''-(1,2-DIETHYLETHYLENE)DIPHENOL 98+%
- rel-4,4'-[(1R,2S)-1,2-Diethyl-1,2-ethanediyl]bisphenol
- 4,4μ-(1,2-Diethylethylene)diphenol, meso-3,4-Bis(4-hydroxyphenyl)hexane, Dihydrodiethylstilbestrol
- [CH(C2H5)C6H4OH]2
- 3,4-BIS-(P-HYDROXYPHENYL)-HEXANE
- 3,4-DI(P-HYDROXYPHENYL)HEXANE
- alpha,alpha’-diethyl-4,4’dihydroxy-bibenzy
- Bibenzyl, alpha,alpha'-diethyl-4,4'-dihydroxy-
- Cycloestrol
- dihydro-stilbestro
- Dihydrostilbestrol
- Estra-Plex
- Estrifar
- Estronal
- Extra-Plex
- gamma,delta-Di(p-hydroxyphenyl)-hexane
- Hexane, 3,4-bis(p-hydroxyphenyl)-
- Hexanoestrol
- Hexestrofen
- Hexron
- Hormoestrol
- meso-3,4-Bis(p-hydroxyphenyl)-n-hexane
- meso-3,4-Di(p-hydroxyphenyl)-n-hexane
- meso-Hexestrol
- NSC-9894
- Phenol, 4,4'-(1,2-diethyl-1,2-ethanediyl)bis-, (R*,S*)-
- Phenol, 4,4'-(1,2-diethyl-1,2-ethylenediyl)bis-, (R*,S*)-
- Phenol, 4,4'-(1,2-diethylethylene)di-
- Phenol, 4,4'-(1,2-diethylethylene)di-, meso-
- Sinestrol
- Stilbestrol, dihydro-
- Synestrol
- Synoestrol
