BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen. S24/25:Berührung mit den Augen und der Haut vermeiden. S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen. S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Sibutramine was introduced as Meridia in the US for the control of
obesity, in conjunction with a reduced-calorie diet. Sibutramine can be prepared
in four steps from 4-chlorobenzyl cyanide. Sibutramine acts as a serotonin and
noradrenaline reuptake inhibitor ; in animal studies, it reduces energy intake by
creating a satieted feeling and increases energy expenditure by enhancing
thermogenesis. In a clinical study in obese patients treated with 10 or 15 mg of
Sibutramine once-daily, meaningful weight loss was sustained for 12 months ;
an additional study demonstrated a lack of abuse potential. An appreciable part
of Sibutramine's effect would also be due to its 2N-mono and didesmethylmetabolites,
which are very potent monoamine reuptake inhibitors
themselves.
Chemische Eigenschaften
White Solid
Verwenden
A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Upstream-Materialien And Downstream Produkte
Sibutramine hydrochloride solution in Methanol,1000ug/ml
Sibutramine Hydrochloride MonohydrateQ: What is
Sibutramine Hydrochloride Monohydrate Q: What is the CAS Number of
Sibutramine Hydrochloride Monohydrate Q: What is the storage condition of
Sibutramine Hydrochloride Monohydrate Q: What are the applications of
Sibutramine Hydrochloride Monohydrate
Sibutramine Hydrochloride CIV (1612845)
SIBUTRAMINE HCL MONOHYDRATE
125494-59-9
C17H19D7ClNHCl
C17H26ClNxHClxH2O
C16H24ClNHCl
C17H26ClNHClH2O
33432
CRESTOR
Intermediates & Fine Chemicals
Pharmaceuticals
Anilines, Aromatic Amines and Nitro Compounds
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