Deflazacort
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- CAS-Nr.
- 14484-47-0
- Bezeichnung:
- Deflazacort
- Englisch Name:
- Deflazacort
- Synonyma:
- oxaz;deflan;Cortax;l-5458;Dezacor;Caltort;Azaeort;azacort;calcort;MDL 458
- CBNumber:
- CB8705963
- Summenformel:
- C25H31NO6
- Molgewicht:
- 441.52
- MOL-Datei:
- 14484-47-0.mol
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Deflazacort Eigenschaften
- Schmelzpunkt:
- 255-256.5°C
- alpha
- D +62.3° (c = 0.5 in chloroform)
- Siedepunkt:
- 595.4±50.0 °C(Predicted)
- Dichte
- 1.41
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥20mg/mL
- pka
- 14.30±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to tan
- Merck
- 14,2862
- InChIKey
- FBHSPRKOSMHSIF-UBRVQRTASA-N
- SMILES
- C12(C(COC(C)=O)=O)[C@]3(C)C(C4C([C@H](C3)O)[C@]3(C)C(=CC(C=C3)=O)CC4)CC1OC(C)=N2
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
S-S?tze: |
24/25 |
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WGK Germany |
3 |
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RTECS-Nr. |
TU4157050 |
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HS Code |
29349990 |
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Toxizit?t |
LD50 orally in mice: 5200 mg/kg (Schiatti) |
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Bildanzeige (GHS) |
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Alarmwort |
Achtung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H360 |
Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Fertility (Fruchtbarkeit) |
Kategorie 1 |
Achtung |
src="/GHS08.jpg" width="20" height="20" /> |
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H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
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Sicherheit |
P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
P314 |
Bei Unwohlsein ?rztlichen Rat einholen / ?rztliche Hilfe hinzuziehen. |
P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Deflazacort Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Deflazacort is an antiinflammatory
treatment of rheumatoid arthritis. Its antirheumatic potency i s similar to that of prednisone, while its hyperglycernic and calcium depleting effects are reportedly less.
Chemische Eigenschaften
Off-White to Pale Yellow Solid
Verwenden
Deflazacort-d3, is the labeled analogue of Deflazacort (D228975), a systemic corticosteroid, and a derivative of prednisolone. Used for rheumatoid arthritis and lupus.
Deflazacort Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Deflazacort Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 487)Lieferanten
14484-47-0(Deflazacort)Verwandte Suche:
- lantadin
- 11b,21-dihydroxy-2'-methyl-5'bh-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetate
- DEFLAZACORT
- Calcort, Deflan, Dezacor, Flantadin, Lantadin
- DECYLACRYLATE
- (11,16)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
- Dezacor
- Flantadin
- Azaeort
- Caltort
- Dezacor:Flantadin
- Lalltadin
- Oxazaoon
- 5'bH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11b,21-dihydroxy-2'-methyl-, 21-acetate
- 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11b,16b)-
- Deflanil
- oxaz
- (1lβ,16β)-21- (Acetyloxy)-11-hydroxy-2’-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
- 16-d)oxazole-3,20-dione,11-beta,21-dihydroxy-2’-5’-beta-h-pregna-4-dieno(17
- azacort
- calcort
- deflan
- (5'β)-11β-Hydroxy-21-acetyloxy-2'-methyl-1,2,4,5-tetradehydropregnano[17,16-d]oxazole-3,20-dione
- (5'β)-21-Acetyloxy-11β-hydroxy-2'-methylpregnano[17,16-d]oxazole-1,4-diene-3,20-dione
- 11b,21-Dihydroxy-2'-
- Denazacort
- 11 BETA 21 DIHYDROXY-2-METHYL-5 BETAH-PREGNA-1,4-DIENO (17,16-D) OXAZOLE-3,20-DIONE21-ACETATE
- 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11β,16β)-
- 11β,21-dihydroxy-2′-methyl-5′βH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 2′-acetate
- pregna-1,4-diene-11β,21-diol-3,20-dione[17α,16α-d]-2′-methyloxazoline 21-acetate
- Deflazacort (100 mg)
- Deflzacort
- Deflazacort solution,100ppm
- Deflazacort-d3
- Deflazacort(Calcort)
- Dezacort
- MDL 458
- (11β,16β)-21-(Acetyloxy)-11-hydroxy-2'-Methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione-d3
- Azacort-d3
- Azacortinol-d3
- Calcort-d3
- Deflan-d3
- Dezacor-d3
- Dezacort-d3
- DL 458IT-d3
- Flantadin-d3
- L 5458-d3
- Lantadin-d3
- MDL 458-d3
- Oxazacort-d3
- Deflazacort, >=98%
- Cortax
- Decortil
- dl-458-it
- l-5458
- Deflazacort>
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- Deflazacor