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ANTI-CORTISOL

ANTI-CORTISOL Struktur
CAS-Nr.
Englisch Name:
ANTI-CORTISOL
Synonyma:
ANTI-CORTISOL;ANTI-HYDROCORTISONE;ANTI-CORTISOL MOUSE MAB;Anti-Cortisol antibody produced in rabbit
CBNumber:
CB8431624
Summenformel:
C21H30O5
Molgewicht:
362.4599
MOL-Datei:
Mol file

ANTI-CORTISOL Eigenschaften

storage temp. 
2-8°C
Aggregatzustand
lyophilized powder

Sicherheit

WGK Germany  3

ANTI-CORTISOL Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Cortisol antibody has been used in Plasma hormone assay and immunofluorescence.

Allgemeine Beschreibung

Cortisol is the principal secretary glucocorticoid of human adrenal cortex. It is produced as cortisone but converted to a biologically active form, cortisol, by the activity of enzyme 11β- hydroxysteroid dehydrogenase (11-HSD).

Biochem/physiol Actions

Cortisol is the principal secretary glucocorticoid of human adrenal cortex. It is produced as cortisone but converted to a biologically active form, cortisol, by the activity of enzyme 11β- hydroxysteroid dehydrogenase (11-HSD). Cortisol is bound to corticosteroid-binding globulin in the plasma. The organs that produce 11-HSD and involved in metabolizing and clearing it from plasma cortisol are kidney and the liver. Cortisol may be oxidised at 11-hydroxt position to result in the production of cortisone, dihydrocortisone, or tetrahydrocortisone. Cortisol and other glucocorticoids bind to the human glucocorticoid receptor (hGR) that is predominantly present in the cytoplasm. On binding, the recptor-ligand complex translocate to nucleus where the transcription of target genes is induced. Deficiency in the levels of 11-HSD are responsible for juvenile hypertension, (a feature of Apparent Mineralocorticoid Excess syndrome), edema, heart failure and hypokalemia (licorice intoxication).

ANTI-CORTISOL Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-CORTISOL Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 17)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80

()Verwandte Suche:


  • ANTI-CORTISOL
  • ANTI-CORTISOL MOUSE MAB
  • ANTI-HYDROCORTISONE
  • Anti-Cortisol antibody produced in rabbit
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