Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)
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- CAS-Nr.
- 9028-48-2
- Bezeichnung:
- Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)
- Englisch Name:
- EC 1.1.1.42
- Synonyma:
- IDH;ICDH;IDH1;MGC55806;MGC171441;MGC174090;EC 1.1.1.42;EC 1.1.1.42 TYPE I;EC 1.1.1.42 TYPE IV;:THREO-DS-ISOCITRATE
- CBNumber:
- CB8395171
- Summenformel:
- NULL
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Eigenschaften
- storage temp.
- 2-8°C
- Aggregatzustand
- solution (clear)
- Farbe
- yellow-brown
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| F |
10 |
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| HS Code |
3507909090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .
Allgemeine Beschreibung
Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.
Biochem/physiol Actions
Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.
Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 59)Lieferanten
9028-48-2(Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat))Verwandte Suche:
Tris(pentan-2,4-dionato)eisen(II)
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium
(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
Phenylselenol
Dichloro(ethylendiamin)platin
(p-Toluolsulfonyl)methylisocyanid
(Pentan-2,4-dionato-O,O')silber
2-Methylpropylisocyanid
Aluminiumtris(2,4-pentandionato-O,O')
Benzylisocyanid
Kupfer(II)-4-oxopent-2-en-2-olat
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium
1,1,3,3-Tetramethylbutylisocyanat
N-Butylisocyanid
Methylisocyanacetat
Ethylisocyanacetat
- THREO-DS-ISOCITRATE: NADP+ OXIDOREDUCTASE
- THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING]
- THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE I
- THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE IV
- isocitrate dehydrogenase from porcine heart
- ICDH
- ISOCITRIC DEHYDROGENASE (NADP)
- ISOCITRIC DEHYDROGENASE (NADP) TYPE I
- ISOCITRIC DEHYDROGENASE (NADP) TYPE IV
- ISOCITRATE DEHYDROGENASE
- EC 1.1.1.42
- EC 1.1.1.42 TYPE I
- EC 1.1.1.42 TYPE IV
- ISOCITRAT DEHYDROGENASE FROM PORCINE HEA RT, 3-8 U/MG
- ISOCITRIC DEHYDROGENASE TYPE IV FROM*POR CINE HEART
- ISOCITRATE DEHYDROGENASE FROM PORCINE HE ART, ~10 U/MG
- ISOCITRIC DEHYDROGENASE TYPE I CRUDE*FRO M PORCINE H
- isocitric dehydrogenase (nadp) from porcine heart
- Recombinant Isocitrate Dehydrogenase
- isocitric dehydrogenase
- ICDH, threo-Ds-Isocitrate: NADP+ oxidoreductase
- Isocitric Dehydrogenase (NADP) from porcine heart,threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH
- Isocitrate dehydrogenase (NAD+) recombinant from Yeast, 50% glycerol solution
- rICDH (NADP), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
- rICDH (NAD), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
- IsoCltrate dehydrogenase
- TPN-specific isocitrate dehydrogenase
- TPN-linked isocitrate dehydrogenase
- TPN-isocitrate dehydrogenase
- TPN-dependent isocitrate dehydrogenase
- Oxalosuccinic decarboxylase
- Isocitrate Dehydrogenase preparation porcine heart
- isocitric dehydrogenase type I crude*from porcine
- Dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate)
- ISOCITRIC DEHYDROGENASE HIGHLY PURIFIED FROM PORCIN
- Isocitrate Dehydrogenase 1 (NADP+) huMan
- IDH
- IDH1
- Isocitrate Dehydrogenase Cytoplasmic
- MGC171441
- MGC174090
- MGC55806
- Isocitric Dehydrogenase (NADP), Bacillus subtilis, recombinant from E. coli
- Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
- NADP-specific isocitric dehydyrogenase
- NADPH-dependent isocitrate dehydrogenase
- Isocitrate Dehydrogenase (NADP+) from Bacteria, Recombinant
- Native Porcine Isocitric Dehydrogenase (NADP)
- Isocitrate Dehydrogenase (NADP+) from Yeast, Recombinant
- Recombinant Human IDH1 C-his8 Protein, His Tag
- Recombinant Human IDH1 Protein, His Tag
- Isocitrate dehydrogenase from Bacillus subtilis, Recombinant
- :THREO-DS-ISOCITRATE
- Isocitrate dehydrogenas
- 9028-48-2
- 1.1.x.x Acting on hydroxyl groups
- Biochemicals and Reagents
- BioChemical
