SIMVASTATIN, SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Simvastatin is a competitive inhibitor of HMG-CoA reductase (K_i = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-κB activation (IC₅₀ = ^~13 μM) and potentiates apoptosis in human myeloid leukemia cells. It also inhibits glutathione peroxidase 4 (GPX4) activity, increases malondialdehyde (MDA) levels, and induces ferroptosis in MDA-MB-231 and MCF-7 breast cancer cells. Formulations containing simvastatin have been used in the treatment of dyslipidemias.

Verwenden

Simvastatin Hydroxy Acid Sodium Salt is a metabolite of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.

SIMVASTATIN, SODIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SIMVASTATIN, SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30241	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10986	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19863	58
Guangzhou PI PI Biotech Inc	020-81716320 +86-13602409664	Sales@pipitech.com	China	3633	55

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• SIMVASTATIN HYDROXY ACID SODIUM SALT
• SIMVASTATIN, SODIUM SALT
• IMp. A (EP) as SodiuM Salt: (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-DiMethylbutanoyl)oxy]-2,6-diMethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid SodiuM Salt (Tenivastatin SodiuM Salt
• Simvastatin Impurity as Sodium Salt
• Simvastati
• SiMvastatin IMp. A (EP) as SodiuM Salt
• sodium,(3R,5S)-7-[(1R,2R,6S,8S)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Simvastatin hydroxyl acid sodium salt-d6
• Simvastatin EP Impurity A Sodium Salt
• FYSMQCWXGBXWLB-VMCZNHHFSA-M
• Sodium (3R,5R)-7-{(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-1-naphthalenyl}-3,5-dihydroxyheptanoate
• Simvastatin Impurity 1(Simvastatin EP Impurity A)
• Simvastatin Impurity 1（EP-A）
• Simvastatin hydroxy acid sodium
• Simvasatin Ep Imp A
• Simvasatin EP Impurity A/ Simvasatin Related Compound A (Simvastatin Sodium/ Tenivastatin Sodium)
• Simvastatin hydroxyl acid D6 Sodium salt
• Simvastatin EP Impurity AQ: What is Simvastatin EP Impurity A Q: What is the CAS Number of Simvastatin EP Impurity A Q: What is the storage condition of Simvastatin EP Impurity A Q: What are the applications of Simvastatin EP Impurity A
• Simvastatin Acid Sodium Salt
• Simvastatin Impurity A sodium salt（EP）
• SimvastatinEPImpurityA-d6SodiumSalt
• Simvastatin Impurity A as Sodium Salt
• Simvastatin EP Impurity A as Sodium Salt
• Simvastatin Impurity 1 Sodium Salt(Simvastatin EP Impurity A Sodium Salt)
• 1-Naphthaleneheptanoic acid,8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,d-dihydroxy-2,6-dimethyl-, monosodium salt, [1S-[1a(bS*,dS*),2a,6b,8b,8aa]]-
• Sodium (3R,5R)-7-((1S,2S,6R,8S,8aR)-8-((2,2-dimethylbutanoyl)oxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate
• 101314-97-0
• 12009-77-6
• C25H39O6Na