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Sacubitril Impurity 7

Sacubitril Impurity 7 Struktur
149709-44-4
CAS-Nr.
149709-44-4
Englisch Name:
Sacubitril Impurity 7
Synonyma:
LBQ657;LCZ696-4;Sacubitrilat;Deethyl Sakuba;LCZ-696 Impurity 1;SACUBITRIL DI ACID;Diacid of Sacubitril;LCZ696 impurities124;LBQ-657(Sacubitrilat);Sacubitrilat (LBQ-657)
CBNumber:
CB83133439
Summenformel:
C22H25NO5
Molgewicht:
383.44
MOL-Datei:
149709-44-4.mol

Sacubitril Impurity 7 Eigenschaften

Siedepunkt:
705.4±60.0 °C(Predicted)
Dichte
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
4.59±0.23(Predicted)
Farbe
White to off-white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Sacubitril Impurity 7 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Sacubitril Impurity 7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sacubitril Impurity 7 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 117)Lieferanten
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Standardpharm Co. Ltd.
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TargetMol Chemicals Inc.

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China National Standard Pharmaceutical Corporation Limited
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Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58

  • LBQ657
  • Sacubitrilat
  • (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
  • LCZ696-4
  • Diacid of Sacubitril
  • LCZ-696 Impurity 1
  • Sacubitrilat (LBQ-657)
  • Sacubitril Desethyl Impurity
  • LCZ696 Impurity 900-04
  • Deethyl Sakuba
  • Sacubitril metabolite LBQ 657
  • [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-
  • 4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid
  • (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci
  • Diacid of Sacubitril/ Sacubitril Desethyl Impurity/ Sacubitrilat
  • LCZ696 impurities124
  • Sacubitril metabolite LBQ 657Q: What is Sacubitril metabolite LBQ 657 Q: What is the CAS Number of Sacubitril metabolite LBQ 657 Q: What is the storage condition of Sacubitril metabolite LBQ 657 Q: What are the applications of Sacubitril metabolite LBQ 657
  • quinoline,6-bromo-7-chloro-
  • SACUBITRIL DI ACID
  • Salcubatra calcium impurity J
  • LBQ-657(Sacubitrilat)
  • (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid
  • Sacubitril metabolite LBQ 657-[d4]
  • Sacubitril Impurity 4 (LBQ-657) (desethyl) (Sacubitrilat)
  • Sacubitril Impurity 4 (LBQ-657) (desethyl) (Sacubitrilat)
  • Valsartan Impurity D-1
  • Sacubitril Diacid Impurity
  • LCZ696 impurity 900-04(LBQ657)
  • 149709-44-4
  • 14709-44-4
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