p-Nitrobenzyl 2-Diazo-3-trimethylsilyloxy-3-butenoate Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
p-Nitrobenzyl 2-Diazo-3-trimethylsilyloxy-3-butenoate is prepared by silylation of the corresponding diazoacetoacetate with a silyl triflate (Trimethylsilyl Trifluoromethanesulfonate or t-Butyldimethylsilyl Trifluoromethanesulfonate) and Triethylamine in CH2Cl2. For large scale preparations the use of Chlorotrimethylsilane, Potassium Iodide (one equivalent), and Et3N in acetonitrile is more advantageous.
p-Nitrobenzyl 2-Diazo-3-trimethylsilyloxy-3-butenoate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte