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6-(octylaMino)pyriMidine-2,4(1H,3H)-dione

6-(octylaMino)pyriMidine-2,4(1H,3H)-dione Struktur
83797-69-7
CAS-Nr.
83797-69-7
Englisch Name:
6-(octylaMino)pyriMidine-2,4(1H,3H)-dione
Synonyma:
6-OAU;CS-2658;GTPL5846;6-OAU, >98%;GTPL5846, >98%;6-OAU(GTPL5846);GTPL-5846 (6-OAU);GTPL 5846;GTPL5846;6-OAU;GTPL-5846;6-(Octylamino)-2,4(1H,3H)-pyrimidinedione;6-(octylaMino)pyriMidine-2,4(1H,3H)-dione
CBNumber:
CB82736888
Summenformel:
C12H21N3O2
Molgewicht:
239.31
MOL-Datei:
83797-69-7.mol

6-(octylaMino)pyriMidine-2,4(1H,3H)-dione Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
≤0.25mg/ml in DMSO;0.25mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
Farbe
Light yellow to yellow
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

6-(octylaMino)pyriMidine-2,4(1H,3H)-dione Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

GPR84 is a Gαi protein-coupled receptor that is activated by medium-chain free fatty acids, but only at micromolar concentrations. GPR84 is expressed in leukocytes and its expression is further induced by LPS. 6-OAU is a synthetic agonist for GPR84 (EC50 = 512 nM). It has insignificant actions at a panel of 69 other receptors, channels, or transporters. 6-OAU promotes chemotaxis in human neutrophils (EC50 = 318 nM) and amplifies TNF-α production by LPS-treated U937 macrophages. In rats, 6-OAU (1 mg/ml) drives the recruitment of neutrophils and macrophages when injected into a subcutaneous air pouch and raises serum levels of CXCL1 (growth-regulated α protein) when delivered intravenously.

6-(octylaMino)pyriMidine-2,4(1H,3H)-dione Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-(octylaMino)pyriMidine-2,4(1H,3H)-dione Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 58)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29884 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32112 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2922 55
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7552 61
Shanghai JiYi Biotechnology Co. Ltd. 13621943973
 sales@shjiyipharmatech.com China 1166 55
  • 6-(octylaMino)pyriMidine-2,4(1H,3H)-dione
  • GTPL5846
  • GTPL-5846 (6-OAU)
  • 6-OAU
  • 6-(Octylamino)-2,4(1H,3H)-pyrimidinedione
  • 6-OAU(GTPL5846)
  • GTPL 5846;GTPL5846;6-OAU;GTPL-5846
  • CS-2658
  • 6-OAU, >98%
  • GTPL5846, >98%
  • 2,4(1H,3H)-Pyrimidinedione, 6-(octylamino)-
  • G protein coupled receptor 84,Inhibitor,IL-8,Sf9,ERK,HEK293,PMN,TNF-α,Lauric acid,MAPKs,U937,GPR84,inflammation,GTPL 5846,B. abortus,Extracellular signal regulated kinases,6 OAU,Cytokines,macrophage,GTPL-5846,6-OAU,6OAU,proinflammatory cytokine,G protein-coupled receptor,GTPγS,chemotaxis,rat air pouch model,inhibit
  • 83797-69-7
  • Inhibitors
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