2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
|
|
|
- CAS-Nr.
- 1041026-71-4
- Englisch Name:
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- Synonyma:
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate;tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1);2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate;6-diazaspiro[3.3]heptane-2-carboxylate oxalate;1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%;1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%;2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1);2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate;ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate;tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
- CBNumber:
- CB82548539
- Summenformel:
- C22H38N4O8
- Molgewicht:
- 486.56
- MOL-Datei:
- 1041026-71-4.mol
|
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Eigenschaften
- Schmelzpunkt:
- 206-209℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- Slightly soluble in water.
- Stabilit?t:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H312 |
Gesundheitssch?dlich bei Hautkontakt. |
Akute Toxizit?t dermal |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P280,P302+P352, P312, P322, P363,P501 |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P321 |
Besondere Behandlung |
|
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
white to yellow Solid.
Verwenden
It is employed as a intermediate for pharmaceutical.
synthetische
Synthesis of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate: Take a 500mL single-necked bottle, add 6-toluenesulfonyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester (7g, 20mmol), dissolve in methanol (200mL), add magnesium chips (3.84 g) g, 0.16 mol, 8 equiv) and stirred at room temperature. The reaction solution gradually turned into a white viscous state with the dissolution of the magnesium scraps, and TLC showed that the reaction of the raw materials was completed. The solvent was removed by rotary evaporation, ether (150 mL) was added, stirred at room temperature for 1 h, filtered through celite, the filtrate was dried over anhydrous sodium sulfate, and an ethanol solution (3 mL) of anhydrous oxalic acid (0.89 g, 9.9 mmol, 0.5 equiv) was added dropwise, A white precipitate appeared immediately, which was filtered under reduced pressure to give 3.2 g of a colorless solid, 82%.
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 175)Lieferanten
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester heMioxylate
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, ethanedioate (2:1)
- 1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%
- tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate, hemioxalate salt
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, heMioxalate
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester ethanedioate
- tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
- 2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate
- 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester, oxalic acid salt
- 2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate
- 2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxalate
- 2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid ethanedioate, 1,1-dimethylethyl ester
- 2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate (2:1)
- 1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%
- 2,6-diazo-heterospiro [3,3] heptane-2-carboxylic acid tert-butyl semicarbamate
- 6-diazaspiro[3.3]heptane-2-carboxylate oxalate
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
- tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1)
- 3-Oxazolidinecarboxylicacid,2,2-dimethyl-4-(2-oxoethyl)-,1,1-dimethylethylester,(10S)-
- 2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1)
- ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
- tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate semioxalate
- 1041026-71-4
- 2C10H18N2O2C2H2O4
