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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Struktur
378247-75-7
CAS-Nr.
378247-75-7
Englisch Name:
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
Synonyma:
Fmoc-7-aminocoumarin-4-acetic acid;Pyridine,2,3,6-trichloro-8-nitro-;N-Fmoc-Aminocoumarin-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid;7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid;[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-
CBNumber:
CB82489625
Summenformel:
C26H19NO6
Molgewicht:
441.43
MOL-Datei:
378247-75-7.mol

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Eigenschaften

Schmelzpunkt:
273-276 °C
Siedepunkt:
660.5±55.0 °C(Predicted)
Dichte
1.418±0.06 g/cm3(Predicted)
storage temp. 
Store at +2°C to +8°C.
pka
4.23±0.10(Predicted)

Sicherheit

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide.

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

ETHYL (3-HYDROXYPHENYL)CARBAMATE 7-Amino-4-carboxymethylcoumarin 3-Aminophenol 9-Fluorenylmethyl chloroformate

Downstream Produkte

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034
 CHINA 3904 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33338 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580
 cooperation@kean-chem.com China 40066 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022
China 4267 65
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050
 cb6@aikonchem.com China 16684 50
Hangzhou Milestone Pharmtech Co., Ltd. 0571-82896630 18969958410
 sales_hz@milestonepharmtech.com China 4853 55
  • [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
  • 2-(7-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-oxo-2H-chroMen-4-yl)acetic acid
  • 7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid
  • 7-N-Fmoc-aminocoumarin-4-acetic acid
  • 2-[7-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-2-oxo-1-benzopyran-4-yl]acetic acid
  • 2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-
  • N-Fmoc-Aminocoumarin-4-acetic acid
  • Fmoc-7-aminocoumarin-4-acetic acid
  • 2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci
  • Pyridine,2,3,6-trichloro-8-nitro-
  • 7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid
  • 7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid
  • 378247-75-7
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