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(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE

(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Struktur
187665-65-2
CAS-Nr.
187665-65-2
Englisch Name:
(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE
Synonyma:
PNU 142633;PNU142633,PNU 142633;(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE;1H-2-Benzopyran-6-carboxamide, 1-[2-[4-[4-(aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-, (1S)-
CBNumber:
CB82454328
Summenformel:
C24H30N4O3
Molgewicht:
422.52
MOL-Datei:
187665-65-2.mol

(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Eigenschaften

Siedepunkt:
652.5±55.0 °C(Predicted)
Dichte
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
L?slichkeit
Soluble to 100 mM in DMSO
Aggregatzustand
Powder
pka
15.27±0.40(Predicted)
Farbe
White to off-white

Sicherheit

(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PNU 142633 is a high affinity SR-1D agonist.

Biologische Aktivit?t

Very selective, high affinity 5-HT 1D receptor agonist (K i values are 6 and > 18000 nM at human 5-HT 1D and 5-HT 1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo .

(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE
  • PNU 142633
  • PNU142633,PNU 142633
  • 1H-2-Benzopyran-6-carboxamide, 1-[2-[4-[4-(aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-, (1S)-
  • 187665-65-2
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