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4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Struktur
114772-55-3
CAS-Nr.
114772-55-3
Englisch Name:
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
Synonyma:
Losartan Impurity 8;1'-Biphenyl]-2-carbonitrile;Benzene,1,3,5-tribromo-2,4,10-trimethyl-;4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-;Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan;4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1;2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole;4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile;2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile;4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
CBNumber:
CB82103743
Summenformel:
C22H22ClN3O
Molgewicht:
379.88
MOL-Datei:
114772-55-3.mol

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Eigenschaften

Schmelzpunkt:
157-158°C
Siedepunkt:
605.6±55.0 °C(Predicted)
Dichte
1.19
storage temp. 
Refrigerator
L?slichkeit
DMSO (Slightly), Ethyl Acetate (Slightly)
pka
13.66±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White

Sicherheit

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Methyl Pentanimidate 4'-Methyl-2-cyanobiphenyl (2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL 3-(4-BROMOBENZYL)-2-BUTYL-4-CHLORO-1H-IMIDAZOL-5-YLMETHANOL Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde 2-(2-METHOXYPHENYL)-4,4-DIMETHYL-2-OXAZOLINE N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE 2-Butyl-4-chloro-5-formylimidazole 4,4-DIMETHYL-2-(4'-METHYL-2-BIPHENYLYL)-2-OXAZOLINE Valeronitril 2-Methoxybenzoylchlorid o-Anissure 4-Bromomethyl-2-cyanobiphenyl

Downstream Produkte

Losartan potassium

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • 4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile
  • Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan
  • 2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
  • 4'-[(2-BUTYL-4-CHLORO-5-HYDROXYMETHYL-1H-IMIDAZOL-1-YL)METHYL]-1,1'-BIPHENYL-2-CARBONITRILE 114772-55-3
  • [1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
  • 4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
  • 4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1
  • 1'-Biphenyl]-2-carbonitrile
  • Losartan Impurity 8
  • 2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile
  • Benzene,1,3,5-tribromo-2,4,10-trimethyl-
  • Losartan Related Compound B 4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1- yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-
  • 4'-[(2-Butyl-4-chloro-5-hydroxymethyl-1H-imidazol-1-yl)methyl]-1,1'-biphenyl-2-carbonitrile
  • 2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole
  • 114772-55-3
  • Losartan Potassium
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