2-Pyridon
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- CAS-Nr.
- 142-08-5
- Bezeichnung:
- 2-Pyridon
- Englisch Name:
- 2-Hydroxypyridine
- Synonyma:
- Pyridin-2(1H)-one;2-PYRIDONE;2(1h)-pyridinone;2-Pyridinol;Pyridin-2-one;2(1H)-PYRIDONE;2-PYRIDON;2-PYRIDOL;Pyridone-2;A-PYRIDONE
- CBNumber:
- CB8137755
- Summenformel:
- C5H5NO
- Molgewicht:
- 95.1
- MOL-Datei:
- 142-08-5.mol
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2-Pyridon Eigenschaften
- Schmelzpunkt:
- 105-107 °C (lit.)
- Siedepunkt:
- 280-281 °C (lit.)
- Dichte
- 1.39
- Brechungsindex
- 1.5939 (estimate)
- Flammpunkt:
- 210 °C
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- 450g/l
- pka
- 0.75(at 20℃)
- Aggregatzustand
- Liquid
- Farbe
- Colorless to yellow to brown, darken on storage with no loss of purity
- Wasserl?slichkeit
- Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
- BRN
- 105786
- LogP
- -0.593 (est)
- CAS Datenbank
- 142-08-5(CAS DataBase Reference)
- NIST chemische Informationen
- 2(1H)-Pyridinone(142-08-5)
- EPA chemische Informationen
- 2(1H)-Pyridinone (142-08-5)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi,Xn,T |
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| R-S?tze: |
36/37/38-40-25 |
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| S-S?tze: |
26-36-37/39-22-45-36/37/39 |
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| RIDADR |
UN2811 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
UV1144050 |
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| F |
8 |
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| TSCA |
Yes |
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| HazardClass |
6.1 |
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| PackingGroup |
III |
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| HS Code |
29333990 |
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| Toxizit?t |
LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
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2-Pyridon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
white to light yellow crystal
Verwenden
2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.
Definition
ChEBI: 2-Hydroxypyridine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. It has a role as a plant metabolite.
Allgemeine Beschreibung
2-Hydroxypyridine, an enolic tautomer of 2-pyridone, belongs to the class of volatile organic compounds (VOCs).
Sicherheitsprofil
Moderately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.
l?uterung methode
Distil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]
2-Pyridon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Pyridon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 591)Lieferanten
142-08-5(2-Pyridon)Verwandte Suche:
- 1-Hydroxy-2-pyridine
- alpha-Pyridone
- Pyridone-2
- AURORA KA-3075
- A-PYRIDONE
- TIMTEC-BB SBB004392
- a-Hydroxypyridine
- 1,2-dihydro-2-oxopyridine
- 1H-2-Pyridone
- 1h-pyridin-2-one
- 2-pyridinone
- 2-PYRIDON
- 2-PYRIDOL
- 2-oxopyridine
- 2-Pyridinol (2-hydroxy-pyridin)
- 2-hydroxypyridine (intermediate of benzoxazole)
- Diydrozylpyridine
- 2-Hydroxypyridine(2-Pyridinol)
- 2-Hydroxypyridine
- 2-Hydroxypyridine, 98+%
- 2-HYDROXYPYRIDINE pure
- 2-Pyridinol
2-Pyridone
- 2-PYRIDINOL FOR SYNTHESIS
- 2-hydroxypyridate
- 2(1H)-Pyridone, 2-Pyridinol
- 2-Hydroxypyridine,97%
- 2-Hydroxypyridine 97%
- 3-Fluoro-4-Methylbenzenethiol, >95%
- Levetiracetam EP Impurity C
- 2-Hydroxypyridine>
- 2-Hydroxypyridine, 98%, for synthesis
- Levetiracetam impurity C CRS
- 2-Hydroxypyridine ISO 9001：2015 REACH
- α-Pyridone
- α-Pyridone (Levetiracetam Impurity)
- Levetiracetam impurities520
- Levetiracetam impurities12
- Levetiracetam-3
- Levetiracetam Impurity 3（Levetiracetam EP Impurity C）
- 2(1h)-pyridinone
- 2(1H)-PYRIDONE
- 2-PYRIDONE
- 2-Pyridinol
- Pyridin-2(1H)-one
- Pyridin-2-one
- 2-HYDROXYPYRIDINE (2(1H)-Pyridinol) >98%
- 142-08-5
- 2762-00-6
- 148-08-5
- C5H4NOH
- C5H5NO
- Building Blocks
- C5
- Pyridines
- Heterocyclic Building Blocks
- Others
- Pyridines
- Pyridine
