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Isoxicam

ISOXICAM Struktur
34552-84-6
CAS-Nr.
34552-84-6
Bezeichnung:
Isoxicam
Englisch Name:
ISOXICAM
Synonyma:
Pacyl;W 8495;Maxicam;Vectren;ISOXICAM;Isoxicamo;Isoxicamum;)-,1,1-dioxide;pacyl(antiinflammatory);Inhibitor,Cyclooxygenase,COX,inhibit,Isoxicam
CBNumber:
CB8101486
Summenformel:
C14H13N3O5S
Molgewicht:
335.34
MOL-Datei:
34552-84-6.mol

Isoxicam Eigenschaften

Schmelzpunkt:
265-271℃
Dichte
1.588
storage temp. 
-20°C Freezer
L?slichkeit
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Aggregatzustand
Solid
pka
4.50±1.00(Predicted)
Farbe
White to Pale Beige

Sicherheit

WGK Germany  2
RTECS-Nr. DL0703000
Toxizit?t LD50 in rats (mg/kg): >5000 orally (Whitehouse)

Isoxicam Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Isoxicam is a non-steroidal antiinflammatory agent useful in the treatment of various forms of rheumatoid arthritis, osteoarthritis and musculoskeletal disorders. It is about one-tenth as potent as its structural relative sudoxicam; its similar long T1/2 (>30 hrs.) allows once-daily dosing.

Verwenden

Isoxicam is used for the same indications as piroxicam. Synonyms for isoxicam are floxicam and maxicam.

Definition

ChEBI: A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Steve s-Johnson syndrome.

Weltgesundheitsorganisation (WHO)

Isoxicam, a nonsteroidal anti-inflammatory agent, was introduced in 1983 for the treatment of rheumatic disorders. By 1985 its use had been associated with serious adverse effects, including four deaths from rare skin reactions. This led to its withdrawal in France followed immediately by the voluntary suspension of marketing worldwide by the major manufacturer.

Isoxicam Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Isoxicam Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 65)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277
marketing_china@spectrumchemical.com China 9658 60
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969
isunpharm@qq.com China 4674 55
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266
China 4574 55
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
lucy@atkchemical.com China 9952 58
Aikon International Limited 025-58859352 18068836627
sales01@aikonchem.com China 15084 58
Angel Pharmatech, Ltd. 17317130613
3358272972@qq.com China 3254 58

34552-84-6(Isoxicam)Verwandte Suche:


  • )-,1,1-dioxide
  • 2h-1,2-benzothiazine-3-carboxamide,4-hydroxy-2-methyl-n-(5-methyl-3-isoxazolyl
  • pacyl(antiinflammatory)
  • ISOXICAM
  • 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
  • Pacyl
  • Vectren
  • W 8495
  • Isoxicamo
  • Isoxicamum
  • Maxicam
  • 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide
  • 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1, 1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxa mide
  • Inhibitor,Cyclooxygenase,COX,inhibit,Isoxicam
  • 4-Hydroxy-2-methyl-N-(5-methylisoxazol-3-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
  • 34552-84-6
  • C14H13N3O5S
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • OCTOPIROX
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