Isopropyl 2-((5-amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Isopropyl 2-((5-amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate is an intermediate of Mobocertinib (isopropyl 2-((5-acrylamido-4-((2-dimethylamino) ethyl) (methyl) amino)-2-methoxyphenyl). The desired mobocertinib was synthesized by reacting this intermediate (0.14 mmol) in DCM with 1-ethyl-3 (3-dimethylpropylamine) carbodiimide (EDCI; 0.28 mmol), Hunig's base (0.42 mmol), and acrylic acid (0.28 mmol)[1].

Isopropyl 2-((5-amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Isopropyl 2-((5-amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Enki Biopharmaceuticals (Shanghai) Limited	+86-0086-2157680326 +8613916707528	yusu@enkibiopharma.com	China	48	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62075	58
Bide Pharmatech Ltd.	400-6005915	sales@picasso-e.com	China	39665	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18478	58

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• 5-Pyrimidinecarboxylic acid, 2-[[5-amino-4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxyphenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
• Isopropyl 2-((5-amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
• 1847465-25-1