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(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat

(-)-4-BROMOTETRAMISOLE OXALATE Struktur
62284-79-1
CAS-Nr.
62284-79-1
Bezeichnung:
(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat
Englisch Name:
(-)-4-BROMOTETRAMISOLE OXALATE
Synonyma:
(-)-P-BROMOTETRAMISOLE OXALATE;(-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE
CBNumber:
CB7709111
Summenformel:
C13H13BrN2O4S
Molgewicht:
373.22
MOL-Datei:
62284-79-1.mol

(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat Eigenschaften

Schmelzpunkt:
192 °C (dec.) (lit.)
Flammpunkt:
87℃
storage temp. 
2-8°C
L?slichkeit
Soluble in Water (up to 10 mg/ml)
Aggregatzustand
liquid
Farbe
White
Optische Aktivit?t
[α]25/D 104°, c = 0.5 in H2O
BRN 
4944883
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 21/22-36/37/38-20/21/22
S-S?tze: 24/25-36/37/39-26
WGK Germany  3
F  10

(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R21/22:Gesundheitssch?dlich bei Berührung mit der Haut und beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.

Chemische Eigenschaften

white to light yellow crystal powde

Biochem/physiol Actions

(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.

(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 117)Lieferanten
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62284-79-1((S)-6-(p-Bromphenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazoloxalat)Verwandte Suche:

  • L-(-)-P-BROMOTETRAMISOLE OXALATE
  • L-P-BROMOTETRAMISOLE OXALATE
  • (-)-P-BROMOTETRAMISOLE OXALATE SALT
  • (-)-P-BROMOLEVAMISOLE OXALATE
  • R 30402
  • (S)-(-)-4-BROMOTETRAMISOLE OXALATE
  • (-)-(S)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE
  • S(-)-6-(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE OXALATE
  • 6-BROMOLEVAMISOLE OXALATE
  • (-)-6(4-BROMOPHENYL)-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE ETHANEDIOATE OXALATE SALT
  • (-)-4-BROMOTETRAMISOLE OXALATE
  • (-)-4-bromotetramisole oxalate salt
  • 6-(4-Bromophenyl)-2,3,5,6-tetrahydro-(6S)-imidazo[2,1-b]thiazole,ethanedioate (1:1)
  • (-)-p-Bromotetramisole oxalate salt, 6-Bromolevamisole oxalate salt, (S)-(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate salt
  • (-)-4-Bromotetramisole oxalate, 6-Bromolevamisole oxalate, S(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
  • L(-)-p-Bromotetramisole oxalate,99%
  • (-)-p-Bromotetramosole Oxalate Salt
  • (-)-p-Bromolevamisole oxalate Ready Made Solution
  • (-)-p-Bromotetramisole oxalate【(S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate】
  • (-)-4-BROMOTETRAMISOLE OXALATE USP/EP/BP
  • Bromotetramisole, L(-) oxalate
  • (-)-4-BROMOTETRAMISOLE OXALATE
  • (-)-P-BROMOTETRAMISOLE OXALATE
  • (S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
  • (-)-p-Bromotetramisole oxalate
  • 62284-79-1
  • C13H13BrN2SO4
  • C11H11BrN2SC2H2O4
  • Specific inhibitor of nonspecific alkaline phosphatase
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Thiazoles
  • Inhibitors
  • chiral
  • API
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