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Cetirizine-d8 (hydrochloride)

Cetirizine-d8 (hydrochloride) Struktur
2070015-04-0
CAS-Nr.
2070015-04-0
Englisch Name:
Cetirizine-d8 (hydrochloride)
Synonyma:
Cetirizine-d8 DiHCl;Cetirizine-d8 (hydrochloride);[2H8]-Cetirizine Dihydrochloride
CBNumber:
CB74814411
Summenformel:
C21H18Cl2D8N2O3
Molgewicht:
433.398034224
MOL-Datei:
2070015-04-0.mol

Cetirizine-d8 (hydrochloride) Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
Methanol: slightly soluble; Water: slightly soluble
Aggregatzustand
A solid
Stabilit?t:
Hygroscopic
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Cetirizine-d8 (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cetirizine-d8 (hydrochloride) is intended for use as an internal standard for the quantification of cetirizine , (R)-cetirizine , and (S)-cetirizine by GC- or LC-MS. Cetirizine is a bioactive carboxylated metabolite of hydroxyzine that acts as a selective histamine H1 receptor antagonist (Ki = 10 nM). As a second generation antihistamine, it is non-sedating due to low lipophilicity, which prevents blood-brain barrier transit. Cetirizine is a racemic mixture composed of equal amounts of two enantiomers, (R)-cetirizine and (S)-cetirizine, with pharmacological activity residing primarily in the (R) isomer. Cetirizine inhibits eosinophil chemotaxis and leukotriene B4 (LTB4; ) release independent from H1 antagonism. It inhibits aerosol histamine-induced bronchospasm in guinea pigs (ED50 = 100 μg/kg, p.o.). Formulations containing cetirizine have been used in the treatment of allergic rhinitis and chronic urticaria.

Verwenden

A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.

Cetirizine-d8 (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Cetirizine-d8 (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 12)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
SIMSON PHARMA LIMITED 		+91-8291074273
k.das@simsonpharma.com India 228 58
Hefei Molake Biotechnology Co., Ltd. 0551-66336380 18956014586
 983438788@qq.com China 2159 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
cjbscvictory 13348960310 13348960310
 3003867561@qq.com China 9911 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195
 sales@tybiochem.com China 6829 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 19703 58
58896805
 7993601name@qq.com CHINA 15620 58
  • Cetirizine-d8 (hydrochloride)
  • Cetirizine-d8 DiHCl
  • [2H8]-Cetirizine Dihydrochloride
  • 2070015-04-0
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