TP-472 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
TP-472 is an inhibitor of bromodomain BRD9 (K
d = 33 nM; EC
50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (K
d = 340 nM in an isothermal titration calorimetry (ITC) assay). See the
Structural Genomic Consortium (SGC) website for more information.
TP-472 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte