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Ningetinib

Ningetinib Struktur
1394820-69-9
CAS-Nr.
1394820-69-9
Englisch Name:
Ningetinib
Synonyma:
CS-2653;CT053PTSA;Ningetinib;Ningetinib(free base);Ningetinib-Tosylate(free base);Vascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGFR,Ningetinib,Axl,Inhibitor;N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide;1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-
CBNumber:
CB73367255
Summenformel:
C31H29FN4O5
Molgewicht:
556.58
MOL-Datei:
1394820-69-9.mol

Ningetinib Eigenschaften

Dichte
1.348±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 2 mg/ml
Aggregatzustand
A crystalline solid
pka
11.00±0.70(Predicted)
Farbe
White to off-white

Sicherheit

Ningetinib Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ningetinib, is a potent, orally bioavailable small molecule tyrosine kinase inhibitor (TKI) with IC50s of 6.7, 1.9 and <1.0 nM for c-Met, VEGFR2 and Axl, respectively.

Ningetinib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ningetinib Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 36)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10986 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097
info@topbiochem.com China 9458 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
 sales-cpd@caerulumpharma.com China 3466 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4566 55
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2988 58
  • CS-2653
  • Ningetinib-Tosylate(free base)
  • Ningetinib
  • Ningetinib(free base)
  • CT053PTSA
  • 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-
  • N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
  • Vascular endothelial growth factor receptor,inhibit,c-Met/HGFR,TAM Receptor,Mer,Tyro3,VEGFR,Ningetinib,Axl,Inhibitor
  • 1394820-69-9
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