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Lotilaner

Lotilaner Struktur
1369852-71-0
CAS-Nr.
1369852-71-0
Englisch Name:
Lotilaner
Synonyma:
Lotilaner;Lotilaner (TP-05);Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor;(S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)a mino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2- carboxamide;2-Thiophenecarboxamide, 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-;(S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylic acid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide
CBNumber:
CB73344768
Summenformel:
C20H14Cl3F6N3O3S
Molgewicht:
596.76
MOL-Datei:
1369852-71-0.mol

Lotilaner Eigenschaften

Dichte
1.66±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO : ≥ 100 mg/mL (167.57 mM)
Aggregatzustand
Solid
pka
12.52±0.46(Predicted)
Farbe
White to off-white

Sicherheit

Lotilaner Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Lotilaner is a representative of the isoxazolines, a new class of insecticides discovered in the 2000s.
Isoxazolines (Afoxolaner, Fluralaner, Lotilaner, and Sarolaner) Isoxazolines are insecticidal and arachnicidal substances that can be given orally, or topically as spot-ons, and act systemically in the blood circulation.
lotilaner (Credeliot), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
Lotilaner, like the other isooxazolines is active against fleas, mites, and ticks. After oral administration or topical application, it can kill fleas rapidly.

Verwenden

Lotilaner is a new member of the isoxazoline class for the treatment of flea and tick infestations in cats.

Indications

Lotilaner is a monthly chewable tablet for the treatment and prevention of fleas and ticks. It is used in dogs and puppies 8 weeks of age or older weighing 4.4 pounds or greater (Elanco, 2019).

Nebenwirkungen

These include weight loss, elevated blood urea nitrogen, increased urination, and diarrhea (Elanco, 2019).

Lotilaner Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lotilaner Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 77)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605
info@millionpharm.com China 252 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 11817 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30239 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040
sales@myuchem.com China 7629 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683
mcbio_sales@163.com China 2251 58
Hainan Mike Biomedical Technology Co., Ltd
+86-15120707353 +86-18876637353
tunanmedicine@hotemail.com China 43 58
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5975 58

  • Lotilaner
  • (S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylic acid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide
  • 2-Thiophenecarboxamide, 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-
  • Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor
  • (S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)a mino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2- carboxamide
  • Lotilaner (TP-05)
  • 1369852-71-0
  • C20H14Cl3F6N3O3S
  • 1
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