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8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Struktur
99295-33-7
CAS-Nr.
99295-33-7
Englisch Name:
8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
Synonyma:
159021;SKF 83566 hydrobromi;SKF 83566 HYDROBROMIDE;nicotine craving|||dorsal striatum|||Inhibitor;(+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1;8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol;1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-;7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide;8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE;8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
CBNumber:
CB7334038
Summenformel:
C17H18BrNO
Molgewicht:
332.23
MOL-Datei:
99295-33-7.mol

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Eigenschaften

storage temp. 
Desiccate at RT
L?slichkeit
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: ≥14 mg/mL
Aggregatzustand
solid
Farbe
light tan

Sicherheit

WGK Germany  3

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Potent and selective D 1 -like dopamine receptor antagonist (K i ~ 0.56 nM for D 1 ; K B = 2 μ M for D 2 ). Also antagonist at the vascular 5-HT 2 receptor (K i = 11 nM). Centrally active following systemic administration in vivo .

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • SKF 83566 HYDROBROMIDE
  • 8-BROMO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL HYDROBROMIDE
  • (+/-)-SKF-83566 HYDROCHLORIDE SELECTIVE DOPAMINE D1
  • (±)-SCH-24543, (±)-7-Bromo-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
  • 1H-3-Benzazepin-7-ol, 8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-
  • 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol
  • 159021
  • SKF 83566 hydrobromi
  • 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
  • 7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol hydrobromide
  • nicotine craving|||dorsal striatum|||Inhibitor
  • 99295-33-7
  • C17H18BrNOHCl
  • C17H18BrNOHBr
  • C17H19Br2NO
  • Dopamine receptor
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