AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE
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- CAS-Nr.
- 131602-53-4
- Englisch Name:
- AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE
- Synonyma:
- Aβ25-35;BETA-AMYLOID;GSNKGAIIGLM;-Amyloid(25-35);β-Amyloid (25-35);BETA-AMYLOID (25-35);β-Amyloid (25-35) TFA;25-35) TRIFLUOROACETATE;β-Amyloid peptide(25-35);AMyloid b-Protein (25-35)
- CBNumber:
- CB7297245
- Summenformel:
- C45H81N13O14S
- Molgewicht:
- 1060.27
- MOL-Datei:
- 131602-53-4.mol
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AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Eigenschaften
- Siedepunkt:
- 1517.3±65.0 °C(Predicted)
- Dichte
- 1.248±0.06 g/cm3(Predicted)
- RTECS-Nr.
- BU7435200
- storage temp.
- -20°C
- L?slichkeit
- insoluble in EtOH; insoluble in H2O; ≥106 mg/mL in DMSO
- Aggregatzustand
- Lyophilized.
- pka
- 3.24±0.10(Predicted)
- Farbe
- Lyophilized White
- Wasserl?slichkeit
- Soluble in water.
- Sequenz
- H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
- InChIKey
- WIHBNMPFWRHGDF-SLVFWPMISA-N
Sicherheit
| WGK Germany |
3 |
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| HS Code |
2930909899 |
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AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Amyloid β-Protein Fragment 25-35 has been used:
- to induce neurotoxicity in cortical cultures
- to induce Alzheimer′s disease in rat model
- to induce apoptosis in mesenchymal stem cells (MSCs)
Allgemeine Beschreibung
Amyloid β-Protein Fragment 25-35 (Aβ25-35) is derived from the amyloid-β protein.amyloid-β protein, which is mapped to human chromosome 21q21. Aβ25-35 lacks the N-terminal domain and the metal binding site and is majorly generated by proteolytic cleavage of Aβ(1?40) peptides. It has a β-sheet and β-turn structure.
Biochem/physiol Actions
Amyloid β-Protein Fragment 25-35 (Aβ25-35) is involved in the pathogenesis of Alzheimer′s disease. Inhibitors of this transition may serve as a potential agent in managing Alzheimer′s disease. It is present in the subiculum and entorhinal cortex neurons of Alzheimer′s brain samples and inclusion-body myositis (IBM) muscle. It binds to receptors present in microglia and is capable of lipid membrane insertion. The functional domain sequence of Aβ comprising of sequence GSNKGAIIGLM elicits neurotrophic and neurotoxic effects. Aβ25-35 exhibits rapid aggregation and displays age dependant neurotoxicity.
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 187)Lieferanten
- Amyloid beta-peptide(25-35)
- AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE
- H-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
- AMYLOID BETA-PEPTIDE (25-35) (HUMAN)
- AMYLOID BETA-PROTEIN FRAGMENT 25-35
- AMYLOID BETA-PROTEIN (25-35)
- AMYLOID-BETA PROTEIN (25-35), HUMAN, MOUSE, RAT
- GSNKGAIIGLM
- GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET
- GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET TRIFLUOROACETATE
- BETA-AMYLOID (25-35)
- BETA-AMYLOID PEPTIDE [25-35], HUMAN
- BETA-AMYLOID, FRAGMENT 25-35
- amyloid B-protein fragment 25-35
- Amyloidb-Peptide(25-35)(human)
- -Amyloid(25-35)
- amyloid β-protein fragment 25-35
- Amyloid β-peptide (25-35) (human)
- AMyloid beta (25-35) huMan
- AMyloid b-Protein (25-35)
- M.W. 1060.27 C45H81N13O14S
- AC-ASN-TRP-CYS-LYS-ARG-GLY-ARG-LYS-GLN-CYS-LYS-THR-HIS-PRO-HIS-NH2: AC-NWCKRGRKQCKTHPH-NH2
- 1: PN: US20030114510 SEQID
- Human beta-amyloid peptide(25-35)
- L-Methionine,glycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-
- AMyloid β-peptide (25-35) (huMan)
- Amyloid beta-Protein Fragment 25-35 >=97% (HPLC)
- β-Amyloid (25-35) TFA
- AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE USP/EP/BP
- β-Amyloid (25-35)
- β-Amyloid peptide(25-35)
- Glycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionine
- AMYLOID BETA-PROTEIN (HUMAN
- 25-35) TRIFLUOROACETATE
- Amyloid beta-Protein (25-35) trifluoroacetate salt
- BETA-AMYLOID
- Aβ25-35
- Amyloid β-Protein Fragment 25-35
- GSNKGAIIGLM(131602 53 4(free base)),GSNKGAIIGLM(131602534(free base))
- β-amyloid peptide,Abeta,inhibit,Inhibitor,Amyloid-β,βAmyloid (2535),β Amyloid (25 35)
- Amyloid β-Protein (25-35) trifluoroacetate salt
- biotinylated?，Biotin-GSNKGAIIGLM
- AMyloid β-peptide (25-35) (huMan)TFA
- β-Amyloid (25-35) (human)
- beta-Amyloid Peptide (25-35) (human), toxic amyloid beta (25-35) protein fragment
- 131602-53-4
- 1932-21-1
- C45H81N13O14S1
- C45H81N13O14S
- C48H81N13O14S
- Neurodegenerative Disease Peptides
- Peptides
- BioChemical
- Amyloid beta Protein Fragments
- Amino Acids and Peptides
- Biochemicals and Reagents
- proteins
- Alzheimers and Neurodegenerative Disease Research
