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(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride

(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Struktur
1333998-21-2
CAS-Nr.
1333998-21-2
Englisch Name:
(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
Synonyma:
2S3R-S Aprepitant;Aprepitant Impurity 4 HCl;Aprepitant Impurity SM3FDY3-1;Aprepitant Impurity SM3FDY3-1 HCl;Des-1,2,4-triazol-3-one-5-methyl (2R,3R,2-(S))-Aprepitant Hydrochloride;(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride;(2R,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride (Aprepitant Impurity)
CBNumber:
CB72669004
Summenformel:
C20H19ClF7NO2
Molgewicht:
473.8121824
MOL-Datei:
1333998-21-2.mol

(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Eigenschaften

Sicherheit

(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Des-1,2,4-triazol-3-one-5-methyl (2R,3R,2-(S))-Aprepitant Hydrochloride is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
China National Standard Pharmaceutical Corporation Limited 		+8615391658522
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ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422
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QUALITY CONTROL SOLUTIONS LTD. 		0755-66853366; 13670046396
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BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14055 65
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412
 3001272453@qq.com China 5047 50
Shanghai Ranxon Chemical Co., Ltd. 13148101715
2073632910@qq.com China 38 55
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978
 1511893459@qq.com China 7850 55
Hubei Yangxin Medical Technology Co., Ltd. 15374522761
 3003392093@qq.com China 8376 55
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199
 wxf@sungening.com China 9577 60
Jinan blalong chemical co. LTD 2710913286@.com
 1513643261@qq.com China 14246 58

1333998-21-2()Verwandte Suche:

  • (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
  • Aprepitant Impurity 4 HCl
  • 2S3R-S Aprepitant
  • Aprepitant Impurity SM3FDY3-1 HCl
  • Aprepitant Impurity SM3FDY3-1
  • Des-1,2,4-triazol-3-one-5-methyl (2R,3R,2-(S))-Aprepitant Hydrochloride
  • (2R,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride (Aprepitant Impurity)
  • 1333998-21-2
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