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ASP 2151

ASP 2151 Struktur
841301-32-4
CAS-Nr.
841301-32-4
Englisch Name:
ASP 2151
Synonyma:
CS-2753;ASP 2151;Amcnamevir;AMenaMevir;Amenamevil;Amenamevir (ASP2151);ASP 2151 (Amenamevir);ASP2151;ASP 2151;ASP-2151;Rosuvastatin Impurity 184;Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
CBNumber:
CB72627341
Summenformel:
C24H26N4O5S
Molgewicht:
482.55
MOL-Datei:
841301-32-4.mol

ASP 2151 Eigenschaften

Dichte
1.360±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM)
Aggregatzustand
A solid
pka
12.60±0.70(Predicted)
Farbe
White to off-white

Sicherheit

ASP 2151 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).

ASP 2151 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ASP 2151 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 76)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018
ramyan@ex-biotech.com CHINA 954 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29815 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289
contact@trustwe.com China 5738 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
+86-86-22-87899925 +86-8618522618860
18522618860@163.com China 694 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 31991 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38460 58

  • ASP 2151
  • AMenaMevir
  • N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide
  • ASP 2151 (Amenamevir)
  • CS-2753
  • ASP2151;ASP 2151;ASP-2151
  • N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide
  • N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide
  • Amenamevir (ASP2151)
  • 2H-Thiopyran-4-carboxamide, N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-, 1,1-dioxide
  • Amcnamevir
  • Herpes simplex virus,Amenamevir,Inhibitor,ASP-2151,HSV,ASP 2151,inhibit
  • Amenamevil
  • Rosuvastatin Impurity 184
  • (2E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic acid 1-methylethyl ester
  • 841301-32-4
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