Hydromorphonhydrochlorid
|
|
|
- CAS-Nr.
- 71-68-1
- Bezeichnung:
- Hydromorphonhydrochlorid
- Englisch Name:
- Hydromorphone hydrochloride
- Synonyma:
- HYDROMORPHONE HCL;dilaudidhydrochloride;Hydromorphine hydrochloride;HYDROMORPHONE HYDROCHLORIDE;XHILEZUETWRSHC-NRGUFEMZSA-N;HYDROMORPHONEHYDROCHLORIDE,USP;dihydromorphinonehydrochloride;Hydromorphone hydrochloride salt;Morphinone, dihydro-, hydrochloride;hydromorphone hydrochloride solution
- CBNumber:
- CB7250921
- Summenformel:
- C17H20ClNO3
- Molgewicht:
- 321.8
- MOL-Datei:
- 71-68-1.mol
|
Hydromorphonhydrochlorid Eigenschaften
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
|
|
| R-S?tze: |
22 |
|
|
| S-S?tze: |
16-36/37-45 |
|
|
| RIDADR |
UN 1230 3/PG 2 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
QD2625000 |
|
|
| HazardClass |
6.1(a) |
|
|
| PackingGroup |
II |
|
|
| HS Code |
2939110000 |
|
|
| Toxizit?t |
LD50 in mice (mg/kg): 61-96 i.v. (Buchwald, Eadie) |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H336 |
Kann Schl?frigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Schl?frigkeit und Benommenheit) |
Warnung |
|
P261, P271, P304+P340, P312,P403+P233, P405, P501 |
|
| Sicherheit |
|
Hydromorphonhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Hydromorphone hydrochloride is a pure opioid agonist with the principal therapeutic activity of analgesia. It has an analgesic potency approximately two to eight times greater than that of morphine and has a rapid onset of action. A significant feature of the analgesia is that it can occur without loss of consciousness.
Chemische Eigenschaften
White Solid
Verwenden
Analgesic (narcotic). Preparation by electrolytic reduction of Morphine.
Controlled substance (opiate).
Clinical Use
Hydromorphone is a potent μ agonist (eight times greater than morphine) that is used to treat severe pain. It is available in intramuscular, intravenous, subcutaneous, oral, and rectal dosage forms. Like all strong μ agonists, hydromorphone is addicting and is a Schedule II drug. Hydromorphone has an oral:parenteral potency ratio of 5:1. The plasma half-lives after parenteral and oral dosage are 2.5 and 4 hours, respectively.
Sicherheitsprofil
Poison by
subcutaneous and intravenous routes.
Experimental teratogenic effects. A
powerful analgesic. When heated to
decomposition it emits very toxic fumes of
NOx and HCl. See also MORPHINE.
Hydromorphonhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
71-68-1(Hydromorphonhydrochlorid)Verwandte Suche:
- morphinan-6-one,4,5-alpha-epoxy-3-hydroxy-17-methyl-,hydrochloride,(5’-alpha
- hydromorphone hydrochloride--dea*schedule ii item
- HYDROMORPHONE HYDROCHLORIDE METHANOL*SOL UTION
- HYDROMORPHONE HYDROCHLORIDE OPIATE ANALG ESIC
- (5α)-4,5-epoxy-3-hydroxy-17-methyl-morphinan-6-one hydrochloride
- hydromorphone hydrochloride solution
- HYDROMORPHONEHYDROCHLORIDE,USP
- Hydromorphine hydrochloride
- Morphinan-6-one, 4,5.alpha.-epoxy-3-hydroxy-17-methyl-, hydrochloride
- Morphinan-6-one, 4,5-epoxy-3-hydroxy-17-methyl-, hydrochloride, (5.alpha.)-
- Morphinone, dihydro-, hydrochloride
- HYDROMORPHONE HCL
- HYDROMORPHONE HYDROCHLORIDE
- HydroMorphone Hydrochloride (CII), USP
- Hydromorphone Hydrochloride CII (50 mg)
- Morphinan-6-one,4,5-epoxy-3-hydroxy-17-Methyl-, hydrochloride (1:1), (5a)-
- 4,5-alpha-epoxy-3-hydroxy-17-methylmorphinan-6-onehydrochloride
- dihydromorphinonehydrochloride
- dilaudidhydrochloride
- XHILEZUETWRSHC-NRGUFEMZSA-N
- Hydromorphone hydrochloride salt
- (4R,4aR,7aR,12bS)-9-hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hydrochloride
- Hydrocodone Hydrogen Tartrate 2.5-Hydrate EP Impurity K as Hydrochloride
- 71-68-1
- HU - HZ
- Analytical Chromatography Product Catalog
- Alphabetic
- Analytical Standards
- Chiral Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
