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(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid

(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid Struktur
203120-17-6
CAS-Nr.
203120-17-6
Englisch Name:
(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid
Synonyma:
Laninamivir;CS-746;R 125489;Lanimivir;Laninamivir-d3;Laninamivir (CS-8958);Laninamivir (Inavir, CS8958, R125489);R-125489,inhibit,Inhibitor,R125489,Influenza Virus,Laninamivir;(4S,5R,6R)-5-AcetaMido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-Methoxypropyl)-5,6-dihydro-4H-pyran-2-;(2R,3R,4S)-3-acetamido-2-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-4-guanidino-3,4-dihydro-2H-pyran-6-carboxylic acid
CBNumber:
CB72485059
Summenformel:
C13H22N4O7
Molgewicht:
346.34
MOL-Datei:
203120-17-6.mol

(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid Eigenschaften

Schmelzpunkt:
>300°C (dec.)
Dichte
1.61
storage temp. 
-20°C Freezer
L?slichkeit
Water (Slightly)
pka
3.81±0.70(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Wasserl?slichkeit
Water : 5 mg/mL (14.44 mM; Need ultrasonic)

Sicherheit

(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Laninamivir octanoate (CS-8958), an ester prodrug form of the neuraminidase (NA) inhibitor laninamivir (R-125489), was approved in Japan in 2010 for treatment of influenza virus infections. Laninamivir octanoate is given by intranasal administration at a 20 mg or 40 mg dose. It has a long half-life in humans such that efficacy can be achieved after only a single dose. In addition to vaccines for immunoprophylaxis, antiviral drugs play an essential role in the treatment of influenza virus infections. Two viral proteins have been targeted for therapeutic intervention: the M2 ion channel and NA.

Verwenden

A new potent labelled neuraminidase

(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 73)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
BOC Sciences
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inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52849 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
PT CHEM GROUP LIMITED
+86-85511178; +86-85511178;
peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49978 58

  • (4S,5R,6R)-5-Acetamido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid
  • (4S,5R,6R)-5-AcetaMido-4-guanidino-6-((1R,2R)-2,3-dihydroxy-1-Methoxypropyl)-5,6-dihydro-4H-pyran-2-
  • R 125489
  • Laninamivir (CS-8958)
  • (2R,3R,4S)-3-acetamido-2-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-4-guanidino-3,4-dihydro-2H-pyran-6-carboxylic acid
  • Laninamivir-d3
  • CS-746
  • Lanimivir
  • D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-O-methyl-
  • Laninamivir (Inavir, CS8958, R125489)
  • Laninamivir
  • R-125489,inhibit,Inhibitor,R125489,Influenza Virus,Laninamivir
  • 203120-17-6
  • C1213CH22N215N2O7
  • C13H22N4O7
  • Amines
  • Anti-virals
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
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