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6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure

Trolox Struktur
53188-07-1
CAS-Nr.
53188-07-1
Bezeichnung:
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure
Englisch Name:
Trolox
Synonyma:
TROLOX;TROLOX;troloxc;TROLOX(R);trolox tm;TROLOXTM C;Trolox(R),97%;Trolox, 97% 1GR;Trolox, 97% 5GR;Trolox Standard
CBNumber:
CB7188583
Summenformel:
C14H18O4
Molgewicht:
250.29
MOL-Datei:
53188-07-1.mol

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Eigenschaften

Schmelzpunkt:
187-189 °C (lit.)
Siedepunkt:
313.42°C (rough estimate)
Dichte
1.0616 (rough estimate)
Brechungsindex
1.4970 (estimate)
storage temp. 
2-8°C
L?slichkeit
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Also soluble in Water at alkalinepH.
Aggregatzustand
Crystalline Powder
pka
3.35±0.20(Predicted)
Farbe
White to faintly beige
BRN 
1384051
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI
InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChIKey
GLEVLJDDWXEYCO-UHFFFAOYSA-N
SMILES
C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1
CAS Datenbank
53188-07-1(CAS DataBase Reference)
EPA chemische Informationen
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
WGK Germany  2
RTECS-Nr. DJ2273000
HS Code  29339900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

white to fainly beige crystalline powder

Definition

ChEBI: A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capa ity of complex mixtures.

Allgemeine Beschreibung

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Mechanism of action

Trolox can protect against oxidative stress, genotoxicity and inflammation induced by CS through ROS scavenging mechanism, and serve as a potential antioxidant prevention strategy against oxidative injury of ATII cells in CS-related lung diseases.

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, methyl ester

Downstream Produkte

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 287)Lieferanten
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53188-07-1(6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure)Verwandte Suche:

  • 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxylicaci
  • troloxc
  • 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
  • (+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID
  • TROLOX(R)
  • TROLOXTM C
  • TIMTEC-BB SBB005933
  • trolox tm
  • (+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYL-CHRO M.-2-CARBOXYL.AC
  • rac-2,5,7,8-Tetramethyl-6-hydroxychroman-2α*-carboxylic acid
  • 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
  • Trolox(R),97%
  • Trolox, 97% 1GR
  • Trolox, 97% 5GR
  • 6-hydroxy-2,5,7,8-tetraMethychroMan-2-caboxylic acid (Trolox)
  • (+/-)-6-Hydroxy-2,5,7,8-tetraMethylchroMane-2-carboxylic acid 97%
  • 53188-07-1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
  • 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
  • 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylicAcid>
  • Trolox Standard
  • 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-
  • 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID ISO 9001：2015 REACH
  • TROLOX
  • TROLOX
  • Ferroptosis,Inhibitor,Apoptosis,Reactive Oxygen Species,inhibit,Trolox
  • 53188-07-1
  • 3188-07-1
  • Heterocyclic Building Blocks
  • Building Blocks
  • Benzopyrans
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