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Asiaticoside

Asiaticoside Struktur
16830-15-2
CAS-Nr.
16830-15-2
Englisch Name:
Asiaticoside
Synonyma:
Asiaticosides;asiaticosid;MADECASSOL;dermatologico;blastoestimulina;2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopy;Ba-2742;CENTELASE;MADECASOL;Meal snow
CBNumber:
CB7109339
Summenformel:
C48H78O19
Molgewicht:
959.12
MOL-Datei:
16830-15-2.mol

Asiaticoside Eigenschaften

Schmelzpunkt:
235-238°C
alpha 
D20 -14° (alc)
Siedepunkt:
1017.5±65.0 °C(Predicted)
Dichte
1.44±0.1 g/cm3(Predicted)
Dampfdruck
0.001Pa at 160℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
L?slichkeit
DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
pka
12.50±0.70(Predicted)
Aggregatzustand
Solid
Farbe
Crystals
Wasserl?slichkeit
99mg/L
InChIKey
WYQVAPGDARQUBT-KRQXBQLUNA-N
LogP
0.44 at 22℃
CAS Datenbank
16830-15-2(CAS DataBase Reference)

Sicherheit

S-S?tze: 24/25
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
RTECS-Nr. YU9625000
1-10
HS Code  29389090

Asiaticoside Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.

Chemische Eigenschaften

White powder

Verwenden

Asiatic Acid is a terpenoid saponin component isolated from Centella asiatica with antioxidant and anti-inflammatory activities. Asiaticoside has been shown to possess strong wound-healing properties and reduces scar formation.

Biologische Aktivit?t

Asiaticoside, a triterpenoid compound from Centella asiatica, has been shown to have anti-inflammatory, anti-renal fibrosis and tissue repair promoting effects. Asiaticoside has been shown through ex vivo and in vivo studies to reduce blood urea nitrogen (BUN) and serum creatinine (Scr) levels in a renal ischemia-reperfusion injury (IRI) model [1]. Meanwhile, Asiaticoside decreased the secretion of IL-6, IL-1β, and TNF-α, but increased the secretion of IL-10 using a dose-dependent manner. Treatment of Raw264.7 cells with lipopolysaccharide (LPS) induced an inflammatory response, but the LPS-induced effect was attenuated by the administration of asiaticoside. In addition, asiaticoside significantly inhibits LPS-induced expression of inducible nitric oxide synthase (iNOS) and promotes expression of the polarisation marker protein arginase 1. It is also a potential candidate for use as a dental wound healing agent with a maximum tolerated concentration of 0.25 mg/ml, and its mechanism of action may be related to increased Col1A1 gene expression [2].

Sicherheitsprofil

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits acrid smoke and fumes. Promoteshealing of wounds.

Asiaticoside Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Asiaticoside Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 494)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi LonierHerb Bio Technology Co Ltd
+86-86-+86-86-029-87551862 +8617702909819
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BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 423 58
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+8618092446649
sarah@tnjone.com China 1143 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-17333973358
sales06@hbduling.cn China 8051 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Hovane Phytochemicals Co., Ltd
+86-17340288373
victor.liu@hovane.com China 32 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+86-18580541567; +8618580541567
sales@zhswyy.com China 301 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58

16830-15-2()Verwandte Suche:


  • ranosyl-(1-4)-o-beta-d-glucopyranosyl-(1-6)-o-beta-d-glucopyranosylester
  • CENTELASE
  • ASIATICOSIDE
  • MADECASOL
  • [6-[[3,4-Dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]oxymethyl]-3,4,5-trihydroxy-oxan-2-yl] (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
  • Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-.alpha.-L-mannopyranosyl-(1?4)-O-.beta.-D-glucopyranosyl-(1?6)-.beta.-D-glucopyranosyl ester, (2.alpha.,3.beta.,4.alpha.)-
  • ASIATICOSIDE(P)
  • Gotu Kola (Centella Asiatica) (40%Asiatisides)
  • Urs-12-en-28-oic acid,2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranos
  • yl-(1→6)- β-D-glucopyranosyl ester, (2α,3β,4α)-
  • O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl (2a,3b,4a)-2,3,23-trihydroxyurs-12-en-28-oate
  • O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl ester, (2a,3b,4a)-
  • (4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid [6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl] ester
  • 2α,3β,23-Trihydroxyurs-12-en-28-oic acid 6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester
  • Ba-2742
  • Centella Asiatica(40%Asiatisides)
  • ASIATICOSIDE hplc
  • ASIATICOSIDE WITH HPLC
  • Asiaticoside,Madecassol
  • Asiaticoside Gotu Kola Extract
  • (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
  • BlastostiMulina
  • EMdecassol
  • Marticassol
  • Asiaticoside (30 mg)
  • Asiaticoside, froM Centella asiatica
  • Meal snow
  • Asiaticoside, >=98%
  • Asiaticoside 16830-15-2
  • Centella asiatica extractTriterpenoid saponins
  • Total Triterpenes of centella asiatica extract
  • Asiaticoside(Single)
  • (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid [(2S,3R,4S
  • Centella asiatica Extract Asiaticoside powder
  • Asiaticoside, 98%, from Centella asiatica (L.) Urb.
  • Asiaticosides 10%-80%
  • Asiaticoside CRS
  • BRN0078195
  • CCRIS8995
  • NSC166062
  • Asiaticoside,90%
  • Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α)-
  • Asiaticoside USP/EP/BP
  • Centella asiatica powder
  • Asiaticoside/Centella asiatica
  • Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α)-
  • 2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopy
  • asiaticosid
  • blastoestimulina
  • dermatologico
  • MADECASSOL
  • Asiaticosides
  • asiaticcoside
  • Asiaticoside (6CI)
  • (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate
  • Centella Total Glucosides, CTG
  • Asiaticoside-RM
  • 16830-15-2
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