N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
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- CAS-Nr.
- 123464-89-1
- Englisch Name:
- N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
- Synonyma:
- SKL843;CS-1012;PNU 282987;PNU282987 HCl;Lanreotide Autogel;PNU 282987(PNU 282987 hydrochloride);PNU 282987 - CAS 123464-89-1 - Calbiochem;N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE;(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride;N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride
- CBNumber:
- CB6847535
- Summenformel:
- C14H17ClN2O
- Molgewicht:
- 264.75058
- MOL-Datei:
- 123464-89-1.mol
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N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Eigenschaften
- Schmelzpunkt:
- 240-242℃
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Soluble in DMSO (up to 25 mg/ml)
- Aggregatzustand
- Off-white solid
- Farbe
- White
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
PNU 282987 is used as an activator of α-7 nicotinic acetylcholine receptor.
Allgemeine Beschreibung
A potent agonist highly selective for α7 nAChRs (K
i = 26 nM). Used in investigating the roles of α7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia.
Biologische Aktivit?t
Highly selective α 7 nAChR agonist (K i = 26 nM) displaying negligible blockade of α 1 β 1 γ δ and α 3 β 4 nAChRs (IC 50 ≥ 60 μ M). Found to be inactive against a panel of 32 receptors at 1 μ M, except 5-HT 3 receptors (K i = 930 nM).
N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 119)Lieferanten
123464-89-1()Verwandte Suche:
- N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
- PNU 282987
- N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride
- N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride PNU 282987
- PNU282987 HCl
- PNU 282987(PNU 282987 hydrochloride)
- CS-1012
- PNU 282987 - CAS 123464-89-1 - Calbiochem
- SKL843
- Lanreotide Autogel
- (R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
- Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-, hydrochloride (1:1)
- 123464-89-1
- C14H17ClN2OHCl
- Inhibitors
- Acetylcholine receptor
