Crisaborole intermediate
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- CAS-Nr.
- 1187188-60-8
- Englisch Name:
- Crisaborole intermediate
- Synonyma:
- Creborol Impurity 28;Crisaborole Impurity 28;Crisaborole Impurity 37;Crisaborole Impurity 59;5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
- CBNumber:
- CB68131269
- Summenformel:
- C14H13BO4
- Molgewicht:
- 256.06
- MOL-Datei:
- 1187188-60-8.mol
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Crisaborole intermediate Eigenschaften
- Siedepunkt:
- 432.1±55.0 °C(Predicted)
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- pka
- 7.05±0.20(Predicted)
Sicherheit
Crisaborole intermediate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Crisaborole intermediate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Crisaborole intermediate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 25)Lieferanten
- 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
- 5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
- Crisaborole Impurity 59
- Crisaborole Impurity 37
- Crisaborole Impurity 28
- Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
- Creborol Impurity 28
- 1187188-60-8
