4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide
CAS-Nr.
1187188-59-5
Englisch Name:
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide
Synonyma:
Crisaborole Impurity 23;Crisaborole Impurity 53;Crisaborole Impurity 11;Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-;4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzamide;4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide
CBNumber:
CB68087742
Summenformel:
C14H12BNO4
Molgewicht:
269.06
MOL-Datei:
1187188-59-5.mol
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Eigenschaften
Schmelzpunkt:
>188°C (dec.)
storage temp.
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
Farbe
Pale Red to Red
Stabilit?t:
Hygroscopic
InChI
InChI=1S/C14H12BNO4/c16-14(17)9-1-3-11(4-2-9)20-12-5-6-13-10(7-12)8-19-15(13)18/h1-7,18H,8H2,(H2,16,17)
InChIKey
BNNSMPLZLMPJQX-UHFFFAOYSA-N
SMILES
C(N)(=O)C1=CC=C(OC2=CC=C3B(O)OCC3=C2)C=C1
Sicherheit
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide is used in the preparation of substituted benzoxaborole and related boron-containing small molecules as anti-inflammatory agents.
Allgemeine Beschreibung
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide, also known as Crisaborole Impurity 11, is an impurity of Crisaborole. Crisaborole topical is used to treat mild to moderate atopic dermatitis (eczema).
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-benzamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 43)Lieferanten
China 41
India 2
Global 43
Benzamide, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
4-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzamide
Crisaborole Impurity 11
4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzamide
Crisaborole Impurity 53
Crisaborole Impurity 23
1187188-59-5
C14H12BNO4