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Senaparib

Senaparib Struktur
1401682-78-7
CAS-Nr.
1401682-78-7
Englisch Name:
Senaparib
Synonyma:
IMP4297;IMP 4297;IMP-4297;Senaparib;Senaparib (IMP-4297);Rotundine Impurity 13;Senaparib（IMP4297，JS109）;5-Fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione;inhibit,poly ADP ribose polymerase,IMP 4297,Inhibitor,breast,pancreatic,IMP-4297,Senaparib,PARP,cancer,PCa;2,4(1H,3H)-Quinazolinedione, 5-fluoro-1-[[4-fluoro-3-[[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl]phenyl]methyl]-
CBNumber:
CB68080026
Summenformel:
C24H20F2N6O3
Molgewicht:
478.45
MOL-Datei:
1401682-78-7.mol

Senaparib Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMSO : 83.33 mg/mL (174.17 mM; Need ultrasonic)
Aggregatzustand
Solid
Farbe
White to off-white

Sicherheit

Senaparib Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Senaparib is a novel and potent PARP1 inhibitor with a unique chemical structure and high inhibitory activity. Research has found that Senaparib not only effectively inhibits the enzymatic activity of PARP1 and PARP2 but also induces the "trapping" of PARP1 on DNA, leading to the stalling of DNA replication forks and double-strand DNA breaks, ultimately causing cell death. This "trapping" effect is considered a key factor in the therapeutic efficacy of PARP1 inhibitors.

Senaparib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Senaparib Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 23)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32072 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38465 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238
 sales@sun-shinechem.com China 977 64
Shanghai Biolang biotechnology Co.,Ltd 17764003753
 2326587775@qq.com China 188 55
Shanghai Biolang biotechnology Co.,Ltd 17764003753
 2326587775@qq.com China 188 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
 2853530910@QQ.com China 8010 62
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2984 58
Wuhan Sun-shine Bio-technology Corporation Limited +86-027-6552-2453
sales@sun-shinechem.com China 727 58
  • Senaparib
  • 2,4(1H,3H)-Quinazolinedione, 5-fluoro-1-[[4-fluoro-3-[[4-(2-pyrimidinyl)-1-piperazinyl]carbonyl]phenyl]methyl]-
  • IMP 4297
  • IMP4297
  • IMP-4297
  • inhibit,poly ADP ribose polymerase,IMP 4297,Inhibitor,breast,pancreatic,IMP-4297,Senaparib,PARP,cancer,PCa
  • Rotundine Impurity 13
  • Senaparib (IMP-4297)
  • 5-Fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione
  • Senaparib（IMP4297，JS109）
  • 1401682-78-7
  • C24H20F2N6O3
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