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1-AZAKENPAULLONE

1-AZAKENPAULLONE Struktur
676596-65-9
CAS-Nr.
676596-65-9
Englisch Name:
1-AZAKENPAULLONE
Synonyma:
azakenpaullone;1-AZAKENPAULLONE;1-Azakenpaullone (1-Akp);1-AZAKENPAULLONE USP/EP/BP;InSolution? 1-Azakenpaullone;1-Azakenpaullone - CAS 676596-65-9 - Calbiochem;InSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem;9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-broMo-7,12-dihydro-
CBNumber:
CB6803762
Summenformel:
C15H10BrN3O
Molgewicht:
328.16
MOL-Datei:
676596-65-9.mol

1-AZAKENPAULLONE Eigenschaften

Schmelzpunkt:
>290°C (dec.)
Siedepunkt:
648.8±50.0 °C(Predicted)
Dichte
1.655±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: >10mg/mL
pka
13.36±0.20(Predicted)
Aggregatzustand
Tan solid
Farbe
gray-brown
InChI
InChI=1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)
InChIKey
NTSBZVCEIVPKBJ-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(Br)C=C2)C2CC(=O)NC3=CC=CN=C3C1=2

Sicherheit

WGK Germany  2

1-AZAKENPAULLONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Tan Solid

Verwenden

A selective inhibitor of glycogen synthase kinase-3β.

Allgemeine Beschreibung

A Kenpaullone (>Cat. No. 422000) analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM). Displays over 100-fold greater selectivity over Cdk1/cyclin B and Cdk5/p25 (IC50 = 2.0 μM and 4.2 μM, respectively). The solid form of this compound (Cat. No. 191500) is also available.

Enzyminhibitor

This cell-permeable protein kinase inhibitor (FW = 328.17 g/mol; CAS 676596-65-9: Solubility: 66 mg/mL DMSO; <1 mg/mL H2O), also named 9-bromo-7,12-dihydro-pyrido[3,2’:2,3]azepino[4,5-b]indol-6(5H)-one, selectively and potently targets glycogen synthase kinase 3β, or GSK3β (IC50 = 18 nM) with 100x less inhibitory action against cyclin-dependent kinases (CDKs). 1-Azakenpaullone has become a gold standard for GSK3 inhibition.

1-AZAKENPAULLONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1-AZAKENPAULLONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 85)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58

676596-65-9()Verwandte Suche:


  • 1-AZAKENPAULLONE
  • 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
  • Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-broMo-7,12-dihydro-
  • InSolution? 1-Azakenpaullone
  • 1-Azakenpaullone 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
  • InSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
  • 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
  • azakenpaullone
  • 1-AZAKENPAULLONE USP/EP/BP
  • 1-Azakenpaullone (1-Akp)
  • Glycogen synthase kinase-3,1 Azakenpaullone,GSK-3,1-Azakenpaullone,1Azakenpaullone,Glycogen synthase kinase 3,Inhibitor,inhibit,1-Akp
  • 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one
  • 676596-65-9
  • C15H10BrN3O
  • All Inhibitors
  • Inhibitors
  • Protein Kinase Inhibitors and Activators
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