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PANCREATIC POLYPEPTIDE, HUMAN

PANCREATIC POLYPEPTIDE, HUMAN Struktur
75976-10-2
CAS-Nr.
75976-10-2
Englisch Name:
PANCREATIC POLYPEPTIDE, HUMAN
Synonyma:
PP, HUMAN;PANCREATIC POLYPEPTIDE;Human pancreatic polypeptide;PANCREATIC POLYPEPTIDE, HUMAN;M.W. 4181.71 C185H287N53O54S2;Pancreatic polypeptide(human) (9CI);PANCREATIC POLYPEPTIDE, HUMAN USP/EP/BP;APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2;Pancreatic Polypeptide human, ≥95% (HPLC);Pancreatic Polypeptide huManPancreatic Polypeptide
CBNumber:
CB6764364
Summenformel:
C185H287N53O54S2
Molgewicht:
4181.71098
MOL-Datei:
75976-10-2.mol

PANCREATIC POLYPEPTIDE, HUMAN Eigenschaften

storage temp. 
-15°C
L?slichkeit
Water: 1 mg/ml
Aggregatzustand
Powder
Farbe
White to off-white
Wasserl?slichkeit
Soluble to 0.70 mg/ml in water

Sicherheit

PANCREATIC POLYPEPTIDE, HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pancreatic polypeptide is an agonist of neuropeptide Y (NPY) receptors that reduces forskolin-induced cAMP accumulation in L-M(TK-) cells recombinantly expressing human and rat Y4 receptors (EC50s = 87.1 and 36.3 pM, respectively). It binds to Y1 and Y5 receptors with Ki values of 19 and 3.9 nM, respectively, for human and 50 and 2.4 nM, respectively, for rhesus monkey receptors. Pancreatic polypeptide also binds to rabbit Y1, Y2, Y4, and Y5 receptors (Kis = 0.39, 0.087, 0.79, and 0.24 nM, respectively). It induces contractile responses in isolated rat colon with EC50 values of 1.6 and 0.7 nM for ascending and descending colon segments, respectively. In vivo, pancreatic polypeptide (0.7-7 nmol, i.c.v.) increases food intake in rats.

PANCREATIC POLYPEPTIDE, HUMAN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


PANCREATIC POLYPEPTIDE, HUMAN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • M.W. 4181.71 C185H287N53O54S2
  • H-ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2
  • APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY-NH2
  • ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2
  • ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2
  • ALA-PRO-LEU-GLU-PRO-VAL-TYR-PRO-GLY-ASP-ASN-ALA-THR-PRO-GLU-GLN-MET-ALA-GLN-TYR-ALA-ALA-ASP-LEU-ARG-ARG-TYR-ILE-ASN-MET-LEU-THR-ARG-PRO-ARG-TYR-NH2 HUMAN
  • PP, HUMAN
  • PANCREATIC POLYPEPTIDE
  • PANCREATIC POLYPEPTIDE, HUMAN
  • H-Ala-Pro-Leu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
  • REF DUPL: H-Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Asp-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
  • Pancreatic Polypeptide huManPancreatic Polypeptide
  • Human pancreatic polypeptide
  • Pancreatic polypeptide(human) (9CI)
  • Pancreatic Polypeptide human, ≥95% (HPLC)
  • PANCREATIC POLYPEPTIDE, HUMAN USP/EP/BP
  • Pancreatic Polypeptide (human) (trifluoroaceate salt)
  • 75976-10-2
  • C185H287N53O54S2
  • Natriuretic Peptides
  • Peptides
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • Peptide
  • Neuropeptide Y (NPY ) receptor
  • Elisa Kit-Mouse Elisa Kit
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